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2018
Mark Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis : Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery
Cukras, Catherine ; Wiley, Henry E. ; Jeffrey, Brett G. ; Sen, H. Nida ; Turriff, Amy ; Zeng, Yong ; Vijayasarathy, Camasamudram ; Marangoni, Dario ; Ziccardi, Lucia and Kjellstrom, Sten ^LU , et al. (2018) In Molecular Therapy 26(9). p.2282-2294
- Contribution to journal › Article
2016
Mark Preclinical Dose-Escalation Study of Intravitreal AAV-RS1 Gene Therapy in a Mouse Model of X-linked Retinoschisis : Dose-Dependent Expression and Improved Retinal Structure and Function
Bush, Ronald A ; Zeng, Yong ; Colosi, Peter ; Kjellström, Sten ^LU ; Hiriyanna, Suja ; Vijayasarathy, Camasamudram ; Santos, Maria ; Li, Jinbo ; Wu, Zhijian and Sieving, Paul A (2016) In Human Gene Therapy 27(5). p.376-389
- Contribution to journal › Article
2009
Mark Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function
Haruta, Masatoshi ; Bush, Ronald A ; Kjellstrom, Sten ^LU ; Vijayasarathy, Camasamudram ; Zeng, Yong ; Le, Yun-Zheng and Sieving, Paul A. (2009) In Proceedings of the National Academy of Sciences of the United States of America 106(23). p.402-9397
- Contribution to journal › Article
Mark Intravitreal delivery of AAV8 retinoschisin results in cell type-specific gene expression and retinal rescue in the Rs1-KO mouse
Park, T K ; Wu, Z ; Kjellstrom, S ^LU ; Zeng, Yong ; Bush, Ronald A ; Sieving, P A and Colosi, Peter (2009) In Gene Therapy 16(7). p.26-916
- Contribution to journal › Article
2008
Mark Synaptic pathology in retinoschisis knockout (Rs1-/y) mouse retina and modification by rAAV-Rs1 gene delivery
Takada, Yuichiro ; Vijayasarathy, Camasamudram ; Zeng, Yong ; Kjellstrom, Sten ^LU ; Bush, Ronald A and Sieving, Paul A. (2008) In Investigative Ophthalmology and Visual Science 49(8). p.86-3677
- Contribution to journal › Article
2007
Mark Retinoschisin gene therapy and natural history in the Rs1h-KO mouse : Long-term rescue from retinal degeneration
Kjellstrom, Sten ^LU ; Bush, Ronald A ; Zeng, Yong ; Takada, Yuichiro and Sieving, Paul A. (2007) In Investigative Ophthalmology and Visual Science 48(8). p.45-3837
- Contribution to journal › Article
2004
Mark RS-1 Gene Delivery to an Adult Rs1h Knockout Mouse Model Restores ERG b-Wave with Reversal of the Electronegative Waveform of X-Linked Retinoschisis
Zeng, Yong ; Takada, Yuichiro ; Kjellstrom, Sten ^LU ; Hiriyanna, Kelaginamane ; Tanikawa, Atsuhiro ; Wawrousek, Eric ; Smaoui, Nizar ; Caruso, Rafael ; Bush, Ronald A and Sieving, Paul A. (2004) In Investigative Ophthalmology and Visual Science 45(9). p.85-3279
- Contribution to journal › Article