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2015
Mark Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design
Fjellström, Ola ; Akkaya, Sibel ; Beisel, Hans-Georg ; Eriksson, Per-Olof ; Erixon, Karl ; Gustafsson, David ; Jurva, Ulrik ; Kang, Daiwu ; Karis, David and Knecht, Wolfgang ^LU , et al. (2015) In PLoS ONE 10(1).
- Contribution to journal › Article
2014
Mark Proteolytic activation of the human epithelial sodium channel by trypsin IV and trypsin I involves distinct cleavage sites
Haerteis, Silke ; Krappitz, Annabel ; Krappitz, Matteus ; Murphy, Jane E ; Bertog, Marko ; Krueger, Bettina ; Nacken, Regina ; Chung, Hyunjae ; Hollenberg, Morley D and Knecht, Wolfgang ^LU , et al. (2014) In The Journal of biological chemistry 289(27). p.19067-19078
- Contribution to journal › Article
2007
Mark Recombinant expression, purification, and kinetic and inhibitor characterisation of human site-1-protease
Bodvard, Kristofer ; Mohlin, Johanna and Knecht, Wolfgang ^LU (2007) In Protein Expression and Purification 51(2). p.308-319
- Contribution to journal › Article
2006
Mark Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating fibrinolysis
Knecht, Wolfgang ^LU ; Willemse, Johan ; Stenhamre, Hanna ; Andersson, Mats ; Berntsson, Pia ; Furebring, Christina ; Harrysson, Anna ; Hager, Ann-Christin Malmborg ; Wissing, Britt-Marie and Hendriks, Dirk , et al. (2006) In The FEBS Journal 273(4). p.778-792
- Contribution to journal › Article
2003
Mark Mosquito has a single multisubstrate deoxyribonucleoside kinase characterized by unique substrate specificity
Knecht, Wolfgang ^LU ; Petersen, Gitte Ebert ; Sandrini, Michael Paolo Bastner ^LU ; Søndergaard, Leif ; Munch-Petersen, Birgitte ^LU and Piskur, Jure ^LU (2003) In Nucleic Acids Research 31(6). p.1665-1672
- Contribution to journal › Article
2002
Mark Plant dihydroorotate dehydrogenase differs significantly in substrate specificity and inhibition from the animal enzymes
Ullrich, Alexandra ; Knecht, Wolfgang ^LU ; Piskur, Jure ^LU and Löffler, Monika (2002) In FEBS Letters 529(2-3). p.346-350
- Contribution to journal › Article
Mark Drosophila melanogaster dihydroorotate dehydrogenase : the N-terminus is important for biological function in vivo but not for catalytic properties in vitro
Löffler, Monika ; Knecht, Wolfgang ^LU ; Rawls, John ; Ullrich, Alexandra and Dietz, Carsten (2002) In Insect Biochemistry and Molecular Biology 32(9). p.1159-1169
- Contribution to journal › Article
Mark A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines
Knecht, Wolfgang ^LU ; Sandrini, Michael P B ^LU ; Johansson, Kenth ; Eklund, Hans ; Munch-Petersen, Birgitte ^LU and Piskur, Jure ^LU (2002) In EMBO Journal 21(7). p.1873-1880
- Contribution to journal › Article
Mark Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation
Knecht, Wolfgang ^LU ; Petersen, Gitte Ebert ; Munch-Petersen, Birgitte ^LU and Piskur, Jure ^LU (2002) In Journal of Molecular Biology 315(4). p.529-540
- Contribution to journal › Article
2001
Mark Structural basis for substrate specificities of cellular deoxyribonucleoside kinases
Johansson, K ; Ramaswamy, S ; Ljungcrantz, C ; Knecht, W ^LU ; Piskur, J ^LU ; Munch-Petersen, B ^LU ; Eriksson, S and Eklund, Hans (2001) In Nature Structural Biology 8(7). p.616-620
- Contribution to journal › Article

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