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- 2003
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Mark
Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system.
(
- Contribution to journal › Article
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Mark
Modeling CNS neurodegeneration by overexpression of disease-causing proteins using viral vectors.
(
- Contribution to journal › Scientific review
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Mark
Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats.
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- Contribution to journal › Article
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Mark
Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus)
(
- Contribution to journal › Article
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Mark
Anterograde delivery of brain-derived neurotrophic factor to striatum via nigral transduction of recombinant adeno-associated virus increases neuronal death but promotes neurogenic response following stroke.
(
- Contribution to journal › Article
- 2002
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Mark
Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer.
(
- Contribution to journal › Article
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Mark
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system
(
- Contribution to journal › Article
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Mark
Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector.
(
- Contribution to journal › Article
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Mark
Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer.
(
- Contribution to journal › Article
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Mark
Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.
(
- Contribution to journal › Article