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2020
Mark Enzyme Evolution : An Epistatic Ratchet versus a Smooth Reversible Transition
Ben-David, Moshe ; Soskine, Misha ; Dubovetskyi, Artem ; Cherukuri, Kesava-Phaneendra ; Dym, Orly ; Sussman, Joel L ; Liao, Qinghua ; Szeler, Klaudia ; Kamerlin, Shina Caroline Lynn ^LU and Tawfik, Dan S (2020) In Molecular biology and evolution 37(4). p.1133-1147
- Contribution to journal › Article
2019
Mark Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme
Yang, Gloria ; Anderson, Dave W ; Baier, Florian ; Dohmen, Elias ; Hong, Nansook ; Carr, Paul D ; Kamerlin, Shina Caroline Lynn ^LU ; Jackson, Colin J ; Bornberg-Bauer, Erich and Tokuriki, Nobuhiko (2019) In Nature Chemical Biology 15(11). p.1120-1128
- Contribution to journal › Article
2018
Mark Evolution of chalcone isomerase from a noncatalytic ancestor
Kaltenbach, Miriam ; Burke, Jason R ; Dindo, Mirco ; Pabis, Anna ; Munsberg, Fabian S ; Rabin, Avigayel ; Kamerlin, Shina C L ^LU ; Noel, Joseph P and Tawfik, Dan S (2018) In Nature Chemical Biology 14(6). p.548-555
- Contribution to journal › Article
2017
Mark BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
Raffel, Simon ; Falcone, Mattia ; Kneisel, Niclas ; Hansson, Jenny ^LU ; Wang, Wei ; Lutz, Christoph ; Bullinger, Lars ; Poschet, Gernot ; Nonnenmacher, Yannic and Barnert, Andrea , et al. (2017) In Nature 551(7680). p.384-388
- Contribution to journal › Article