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2018
Mark A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity
Kirby, Ilsa T ; Kojic, Ana ; Arnold, Moriah R ; Thorsell, Ann-Gerd ; Karlberg, Tobias ^LU ; Vermehren-Schmaedick, Anke ; Sreenivasan, Raashi ; Schultz, Carsten ; Schüler, Herwig ^LU and Cohen, Michael S (2018) In Cell Chemical Biology 25(12). p.12-1553
- Contribution to journal › Article
Mark Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14
Holechek, Jacob ; Lease, Robert ; Thorsell, Ann-Gerd ; Karlberg, Tobias ^LU ; McCadden, Caitlin ; Grant, Ryan ; Keen, Abby ; Callahan, Evan ; Schüler, Herwig ^LU and Ferraris, Dana (2018) In Bioorganic & Medicinal Chemistry Letters 28(11). p.2050-2054
- Contribution to journal › Article
Mark Identification of Poly(ADP-Ribose) Polymerase Macrodomain Inhibitors Using an AlphaScreen Protocol
Ekblad, Torun ; Verheugd, Patricia ; Lindgren, Anders E ; Nyman, Tomas ; Elofsson, Mikael and Schüler, Herwig ^LU (2018) In SLAS Discovery 23(4). p.353-362
- Contribution to journal › Article
2017
Mark Design and synthesis of potent inhibitors of the mono(ADP-ribosyl)transferase, PARP14
Upton, Kristen ; Meyers, Matthew ; Thorsell, Ann-Gerd ; Karlberg, Tobias ^LU ; Holechek, Jacob ; Lease, Robert ; Schey, Garrett ; Wolf, Emily ; Lucente, Adrianna and Schüler, Herwig ^LU , et al. (2017) In Bioorganic & Medicinal Chemistry Letters 27(13). p.2907-2911
- Contribution to journal › Article
Mark Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors
Thorsell, Ann-Gerd ; Ekblad, Torun ; Karlberg, Tobias ^LU ; Löw, Mirjam ; Pinto, Ana Filipa ; Trésaugues, Lionel ; Moche, Martin ; Cohen, Michael S and Schüler, Herwig ^LU (2017) In Journal of Medicinal Chemistry 60(4). p.1262-1271
- Contribution to journal › Article
Mark Small Molecule Microarray Based Discovery of PARP14 Inhibitors
Peng, Bo ; Thorsell, Ann-Gerd ; Karlberg, Tobias ^LU ; Schüler, Herwig ^LU and Yao, Shao Q (2017) In Angewandte Chemie (International edition) 56(1). p.248-253
- Contribution to journal › Article
2013
Mark Pharmacology of ADP-ribosylation
Schüler, Herwig ^LU and Ziegler, Mathias (2013) In The FEBS Journal 280(15). p.3542-3542
- Contribution to journal › Article
2012
Mark Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
Wahlberg, Elisabet ; Karlberg, Tobias ^LU ; Kouznetsova, Ekaterina ; Markova, Natalia ^LU ; Macchiarulo, Antonio ; Thorsell, Ann-Gerd ; Pol, Ewa ; Frostell, Åsa ; Ekblad, Torun and Öncü, Delal , et al. (2012) In Nature Biotechnology 30(3). p.8-283
- Contribution to journal › Article