Antiproliferative effects of curcumin analog L49H37 in pancreatic stellate cells: a comparative study.
(2015) In Annals of Gastroenterology 28(3). p.391-398- Abstract
- Pancreatic cancer is a devastating disease with poor prognosis. It is characterized by a pronounced stromal reaction, which resists chemotherapeutics and effective tumor treatment. Pancreatic stellate cells (PSCs) are mainly responsible for this stromal reaction. Moreover, the cancer and stromal interaction seems to promote tumor proliferation. In this study, L49H37, a newly synthesized curcumin analog, was used as intervention to target the stromal compartment of pancreatic cancer.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7751379
- author
- Gundewar, Chinmay LU ; Ansari, Daniel LU ; Tang, Longguang ; Wang, Yi ; Liang, Guang ; Rosendahl, Ann LU ; Saleem, Moin A and Andersson, Roland LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Annals of Gastroenterology
- volume
- 28
- issue
- 3
- pages
- 391 - 398
- publisher
- Hellenic Society of Gastroenterology
- external identifiers
-
- pmid:26129848
- scopus:84931376925
- ISSN
- 1108-7471
- project
- Pancreatic cancer
- language
- English
- LU publication?
- yes
- id
- df1d2b15-54c9-43bf-896b-d6501ce13db5 (old id 7751379)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26129848?dopt=Abstract
- date added to LUP
- 2016-04-04 09:16:09
- date last changed
- 2022-02-20 23:59:55
@article{df1d2b15-54c9-43bf-896b-d6501ce13db5, abstract = {{Pancreatic cancer is a devastating disease with poor prognosis. It is characterized by a pronounced stromal reaction, which resists chemotherapeutics and effective tumor treatment. Pancreatic stellate cells (PSCs) are mainly responsible for this stromal reaction. Moreover, the cancer and stromal interaction seems to promote tumor proliferation. In this study, L49H37, a newly synthesized curcumin analog, was used as intervention to target the stromal compartment of pancreatic cancer.}}, author = {{Gundewar, Chinmay and Ansari, Daniel and Tang, Longguang and Wang, Yi and Liang, Guang and Rosendahl, Ann and Saleem, Moin A and Andersson, Roland}}, issn = {{1108-7471}}, language = {{eng}}, number = {{3}}, pages = {{391--398}}, publisher = {{Hellenic Society of Gastroenterology}}, series = {{Annals of Gastroenterology}}, title = {{Antiproliferative effects of curcumin analog L49H37 in pancreatic stellate cells: a comparative study.}}, url = {{http://www.ncbi.nlm.nih.gov/pubmed/26129848?dopt=Abstract}}, volume = {{28}}, year = {{2015}}, }