Developing a route towards palustrine synthesis
(2016) KEMP31 20152Department of Chemistry
- Abstract
- Palustrine, a piperidine alkaloid, was retrosynthetically analyzed and two branches of a route to a key
intermediate aziridine tried – namely, nitrene formation through UV irradiation and 1,3-dipolar
cycloaddition. Neither approach gave any positive results. After this the synthesis of a model
compound was attempted, but ran into unexpected problems with performing radical terminal
bromination of sorbates. The project overall achieved no notable positive results. - Popular Abstract
- Palustrine is a substance found in a swamp plant. It is harmful to animals, and so we need to study it and its harmful effects to keep us and other animals safe. To do this, first we need to have a reasonable amount of palustrine. Extracting substances from plant matter is often expensive and uses a lot of chemicals harmful to the environment. This project aimed to develop a method to synthesize palustrine from simple molecules, so we wouldn't have to extract it from the plants. Two different ways were tried to make it. One of the ways uses heating, the other one irradiation with UV light. Sadly, neither of these ways worked and the overall result of the project was negative.
Please use this url to cite or link to this publication:
http://lup.lub.lu.se/student-papers/record/8564590
- author
- Veidenberg, Indrek LU
- supervisor
- organization
- course
- KEMP31 20152
- year
- 2016
- type
- L3 - Miscellaneous, Projetcs etc.
- subject
- keywords
- organic chemistry, organisk kemi
- language
- English
- id
- 8564590
- date added to LUP
- 2016-04-29 10:50:38
- date last changed
- 2016-04-29 10:50:38
@misc{8564590, abstract = {{Palustrine, a piperidine alkaloid, was retrosynthetically analyzed and two branches of a route to a key intermediate aziridine tried – namely, nitrene formation through UV irradiation and 1,3-dipolar cycloaddition. Neither approach gave any positive results. After this the synthesis of a model compound was attempted, but ran into unexpected problems with performing radical terminal bromination of sorbates. The project overall achieved no notable positive results.}}, author = {{Veidenberg, Indrek}}, language = {{eng}}, note = {{Student Paper}}, title = {{Developing a route towards palustrine synthesis}}, year = {{2016}}, }