Effects of plant polar lipids on postprandial glycemic regulation in healthy humans
(2022) KNLM01 20221Food Technology and Nutrition (M.Sc.)
- Abstract
- In light of diabetes becoming a global discussion topic, some steps ought to be taken to help reduce the number of individuals suffering from the disease. Keeping good glycemic control through a healthy diet helps prevent diabetes and cardiovascular disease. Plant lipids are increasingly being studied for their postprandial effects on humans. Using a randomized cross-over dose-effect design based on one previous study, which found that high amounts of polar lipids may beneficially affect postprandial blood glucose and insulin concentrations, this study tested whether a lower level of polar lipids can have the same effect on glycemic regulation. For this study, 17 healthy subjects aged 20-40 years with BMIs ranging from 19 to 28 kg/m2 were... (More)
- In light of diabetes becoming a global discussion topic, some steps ought to be taken to help reduce the number of individuals suffering from the disease. Keeping good glycemic control through a healthy diet helps prevent diabetes and cardiovascular disease. Plant lipids are increasingly being studied for their postprandial effects on humans. Using a randomized cross-over dose-effect design based on one previous study, which found that high amounts of polar lipids may beneficially affect postprandial blood glucose and insulin concentrations, this study tested whether a lower level of polar lipids can have the same effect on glycemic regulation. For this study, 17 healthy subjects aged 20-40 years with BMIs ranging from 19 to 28 kg/m2 were recruited. In random order, five different breakfasts were consumed by participants. Three of the breakfasts contained variable amounts of a preparation rich in plant polar lipids (5g, 10g, and 15g) consumed with white wheat bread. In addition, one breakfast contained white wheat bread without added lipids, and another breakfast consisted of rapeseed oil (15g fat) and white wheat bread; these last breakfasts were included as reference meals. In contrast to the previous study, no significant differences between the breakfasts were found in terms of their effect on postprandial glycemic regulation.
The study of the effects of polar lipids on this function is still relatively new. To draw a more solid conclusion, there is a need for more studies to explore polar lipids' ability to regulate postprandial glycemic responses. The results of this study may provide some new directions for future research, such as increasing the number of participants, studying the effects of different sources of polar lipid and trying to use different ways to prepare plant polar lipid-based food. (Less) - Popular Abstract
- A growing number of people are adapting to a sedentary lifestyle and eating highly processed foods (excess sugar and oil) in modern life. Obesity is associated with these habits and is becoming a global health issue leading to diabetes, which is among the top ten causes of death, according to the World Health Organization. Studies suggest that diet is an effective way to regulate glycemia, thereby reducing the risk of diabetes and cardiovascular diseases related to it. Besides conventional products for diabetes patients, such as non-starchy vegetables and whole grains, more recent research focuses on products containing healthy oils to regulate postprandial, which means after meals, blood glucose, and insulin responses. An extract of... (More)
- A growing number of people are adapting to a sedentary lifestyle and eating highly processed foods (excess sugar and oil) in modern life. Obesity is associated with these habits and is becoming a global health issue leading to diabetes, which is among the top ten causes of death, according to the World Health Organization. Studies suggest that diet is an effective way to regulate glycemia, thereby reducing the risk of diabetes and cardiovascular diseases related to it. Besides conventional products for diabetes patients, such as non-starchy vegetables and whole grains, more recent research focuses on products containing healthy oils to regulate postprandial, which means after meals, blood glucose, and insulin responses. An extract of lipids from plants has been shown to have a lowering effect on glycemia in healthy individuals. This study focused on a special type of plant lipid - polar lipids. This study investigated two parameters: postprandial blood glucose and insulin concentrations. The results of this study may be useful for the development of foods containing polar lipids that prevent diabetes.
For the purposes of this investigation, 17 healthy subjects were enrolled in a clinical meal study. For all subjects, three different breakfasts with different concentrations of polar lipids and two reference breakfasts, white wheat bread and rapeseed oil, were prepared. It took around ten weeks to complete the experiments.
In this study, participants were required to arrive at the clinical site at 8 am after they had fasted overnight. Blood samples were collected from participants after they consumed breakfast during the three-hour trial experiment to measure blood glucose and insulin concentrations. A statistical analysis program was used to analyze the data.
According to the results, plant polar lipids do not have a statistically significant effect on after-meal blood glucose or insulin concentration. However, a clear trend can be seen that plant polar lipids can decrease insulin response following breakfast consumption. In order to improve the study, more studies could be conducted with some changes to the experiment design in an effort to understand the function of plant polar lipids.
Moreover, following the results from this research, it can be inferred that supplementing the diet with certain amounts of plant polar lipids may have the potential to stabilize insulin concentration in healthy individuals, thereby reducing the risk of obesity, cardiovascular disease, and other complications associated with them. (Less)
Please use this url to cite or link to this publication:
http://lup.lub.lu.se/student-papers/record/9089100
- author
- Yao, Yijia LU
- supervisor
-
- Juscelino Tovar LU
- Anne Nilsson LU
- organization
- course
- KNLM01 20221
- year
- 2022
- type
- H2 - Master's Degree (Two Years)
- subject
- keywords
- plant polar lipid, meal study, clinical study, postprandial glycemic regulation, applied nutrition and food chemistry
- language
- English
- id
- 9089100
- date added to LUP
- 2022-06-17 11:55:49
- date last changed
- 2022-06-17 11:55:49
@misc{9089100,
abstract = {{In light of diabetes becoming a global discussion topic, some steps ought to be taken to help reduce the number of individuals suffering from the disease. Keeping good glycemic control through a healthy diet helps prevent diabetes and cardiovascular disease. Plant lipids are increasingly being studied for their postprandial effects on humans. Using a randomized cross-over dose-effect design based on one previous study, which found that high amounts of polar lipids may beneficially affect postprandial blood glucose and insulin concentrations, this study tested whether a lower level of polar lipids can have the same effect on glycemic regulation. For this study, 17 healthy subjects aged 20-40 years with BMIs ranging from 19 to 28 kg/m2 were recruited. In random order, five different breakfasts were consumed by participants. Three of the breakfasts contained variable amounts of a preparation rich in plant polar lipids (5g, 10g, and 15g) consumed with white wheat bread. In addition, one breakfast contained white wheat bread without added lipids, and another breakfast consisted of rapeseed oil (15g fat) and white wheat bread; these last breakfasts were included as reference meals. In contrast to the previous study, no significant differences between the breakfasts were found in terms of their effect on postprandial glycemic regulation.
The study of the effects of polar lipids on this function is still relatively new. To draw a more solid conclusion, there is a need for more studies to explore polar lipids' ability to regulate postprandial glycemic responses. The results of this study may provide some new directions for future research, such as increasing the number of participants, studying the effects of different sources of polar lipid and trying to use different ways to prepare plant polar lipid-based food.}},
author = {{Yao, Yijia}},
language = {{eng}},
note = {{Student Paper}},
title = {{Effects of plant polar lipids on postprandial glycemic regulation in healthy humans}},
year = {{2022}},
}