Controlled trial of a short and a prolonged course with ciprofloxacin in patients undergoing transurethral prostatic surgery
(1987) In European Journal of Clinical Microbiology and Infectious Diseases 6(1). p.11-17- Abstract
- The efficacy of a short (Group I) and a prolonged (Group II) course with ciprofloxacin was assessed in patients undergoing transurethral prostatic resection for benign hyperplasia or cancer of the prostate and compared with that of controls without antibiotic (Group III). Both regiments significantly reduced the frequency of postoperative bacteriuria (p less than 0.01) and of severe infectious complications (p = 0.004) as compared to the controls. Both regimens were equally effective in preventing perioperative and postoperative acquisition of bacteriuria in patients without bacteriuria at surgery. In patients with bacteriuria before surgery, bacteriuria was found postoperatively in 35% in Group I and 10% in Group II (p = 0.012), but in... (More)
- The efficacy of a short (Group I) and a prolonged (Group II) course with ciprofloxacin was assessed in patients undergoing transurethral prostatic resection for benign hyperplasia or cancer of the prostate and compared with that of controls without antibiotic (Group III). Both regiments significantly reduced the frequency of postoperative bacteriuria (p less than 0.01) and of severe infectious complications (p = 0.004) as compared to the controls. Both regimens were equally effective in preventing perioperative and postoperative acquisition of bacteriuria in patients without bacteriuria at surgery. In patients with bacteriuria before surgery, bacteriuria was found postoperatively in 35% in Group I and 10% in Group II (p = 0.012), but in 82% of the patients in Group III. Ciprofloxacin inhibited all but 7 of 176 bacterial strains at an MIC of less than or equal to 1 microgram/ml. Given orally ciprofloxacin is a valuable alternative antimicrobial for use in conjunction with transurethral prostatic resection. A short course is sufficient for prophylaxis, and adequate therapy is achieved with a prolonged regimen. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1103783
- author
- Grabe, Magnus LU ; Forsgren, Arne LU ; Björk, Thomas LU and Hellsten, Sverker LU
- organization
- publishing date
- 1987
- type
- Contribution to journal
- publication status
- published
- subject
- in
- European Journal of Clinical Microbiology and Infectious Diseases
- volume
- 6
- issue
- 1
- pages
- 11 - 17
- publisher
- Springer
- external identifiers
-
- pmid:3569248
- scopus:0023112882
- ISSN
- 0722-2211
- DOI
- 10.1007/BF02097183
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Clinical Microbiology, Malmö (013011000), Pediatrics/Urology/Gynecology/Endocrinology (013240400), Division of Urological Cancers (013243420), Urology (013243400)
- id
- bf10cef2-47ff-4f90-b59c-3ab5dc6d00df (old id 1103783)
- date added to LUP
- 2016-04-01 16:52:27
- date last changed
- 2021-09-21 10:01:07
@article{bf10cef2-47ff-4f90-b59c-3ab5dc6d00df, abstract = {{The efficacy of a short (Group I) and a prolonged (Group II) course with ciprofloxacin was assessed in patients undergoing transurethral prostatic resection for benign hyperplasia or cancer of the prostate and compared with that of controls without antibiotic (Group III). Both regiments significantly reduced the frequency of postoperative bacteriuria (p less than 0.01) and of severe infectious complications (p = 0.004) as compared to the controls. Both regimens were equally effective in preventing perioperative and postoperative acquisition of bacteriuria in patients without bacteriuria at surgery. In patients with bacteriuria before surgery, bacteriuria was found postoperatively in 35% in Group I and 10% in Group II (p = 0.012), but in 82% of the patients in Group III. Ciprofloxacin inhibited all but 7 of 176 bacterial strains at an MIC of less than or equal to 1 microgram/ml. Given orally ciprofloxacin is a valuable alternative antimicrobial for use in conjunction with transurethral prostatic resection. A short course is sufficient for prophylaxis, and adequate therapy is achieved with a prolonged regimen.}}, author = {{Grabe, Magnus and Forsgren, Arne and Björk, Thomas and Hellsten, Sverker}}, issn = {{0722-2211}}, language = {{eng}}, number = {{1}}, pages = {{11--17}}, publisher = {{Springer}}, series = {{European Journal of Clinical Microbiology and Infectious Diseases}}, title = {{Controlled trial of a short and a prolonged course with ciprofloxacin in patients undergoing transurethral prostatic surgery}}, url = {{http://dx.doi.org/10.1007/BF02097183}}, doi = {{10.1007/BF02097183}}, volume = {{6}}, year = {{1987}}, }