Resistance to fluoroquinolones in Pseudomonas aeruginosa and Klebsiella pneumoniae
(1994) In Scandinavian Journal of Infectious Diseases 26(3). p.317-320- Abstract
- The fluoroquinolone sensitivity of Pseudomonas aeruginosa and Klebsiella pneumoniae was studied by determinations of Minimum Inhibitory Concentrations (MICs) of norfloxacin and ciprofloxacin in consecutive clinical isolates. In P. aeruginosa, resistance or reduced susceptibility (MIC > or = 8 mg/l for norfloxacin and > or = 2 mg/l for ciprofloxacin) was found in 17% (9/54) of the isolates. Reduced susceptibility (MIC > or = 2 mg/l for norfloxacin) was found in 12% (10/84) of K. pneumoniae isolates. P. aeruginosa strains isolated in 1991 had reduced susceptibility to both norfloxacin and ciprofloxacin significantly more often than isolates from 1984-85 (p = 0.02). 10/84 K. pneumoniae strains from 1991 had reduced susceptibility to... (More)
- The fluoroquinolone sensitivity of Pseudomonas aeruginosa and Klebsiella pneumoniae was studied by determinations of Minimum Inhibitory Concentrations (MICs) of norfloxacin and ciprofloxacin in consecutive clinical isolates. In P. aeruginosa, resistance or reduced susceptibility (MIC > or = 8 mg/l for norfloxacin and > or = 2 mg/l for ciprofloxacin) was found in 17% (9/54) of the isolates. Reduced susceptibility (MIC > or = 2 mg/l for norfloxacin) was found in 12% (10/84) of K. pneumoniae isolates. P. aeruginosa strains isolated in 1991 had reduced susceptibility to both norfloxacin and ciprofloxacin significantly more often than isolates from 1984-85 (p = 0.02). 10/84 K. pneumoniae strains from 1991 had reduced susceptibility to norfloxacin, compared with 1/34 from 1984-85. This difference was not statistically significant (p = 0.11). (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1108135
- author
- Rydberg, Johan LU ; Larsson, Charlotte U LU and Miörner, Håkan LU
- organization
- publishing date
- 1994
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Journal of Infectious Diseases
- volume
- 26
- issue
- 3
- pages
- 317 - 320
- publisher
- Informa Healthcare
- external identifiers
-
- pmid:7939432
- scopus:0028237961
- ISSN
- 1651-1980
- DOI
- 10.3109/00365549409011801
- language
- English
- LU publication?
- yes
- id
- 52d7b9d2-67cd-44be-840b-f8da0b96057f (old id 1108135)
- date added to LUP
- 2016-04-01 16:57:30
- date last changed
- 2021-01-03 04:19:52
@article{52d7b9d2-67cd-44be-840b-f8da0b96057f, abstract = {{The fluoroquinolone sensitivity of Pseudomonas aeruginosa and Klebsiella pneumoniae was studied by determinations of Minimum Inhibitory Concentrations (MICs) of norfloxacin and ciprofloxacin in consecutive clinical isolates. In P. aeruginosa, resistance or reduced susceptibility (MIC > or = 8 mg/l for norfloxacin and > or = 2 mg/l for ciprofloxacin) was found in 17% (9/54) of the isolates. Reduced susceptibility (MIC > or = 2 mg/l for norfloxacin) was found in 12% (10/84) of K. pneumoniae isolates. P. aeruginosa strains isolated in 1991 had reduced susceptibility to both norfloxacin and ciprofloxacin significantly more often than isolates from 1984-85 (p = 0.02). 10/84 K. pneumoniae strains from 1991 had reduced susceptibility to norfloxacin, compared with 1/34 from 1984-85. This difference was not statistically significant (p = 0.11).}}, author = {{Rydberg, Johan and Larsson, Charlotte U and Miörner, Håkan}}, issn = {{1651-1980}}, language = {{eng}}, number = {{3}}, pages = {{317--320}}, publisher = {{Informa Healthcare}}, series = {{Scandinavian Journal of Infectious Diseases}}, title = {{Resistance to fluoroquinolones in Pseudomonas aeruginosa and Klebsiella pneumoniae}}, url = {{http://dx.doi.org/10.3109/00365549409011801}}, doi = {{10.3109/00365549409011801}}, volume = {{26}}, year = {{1994}}, }