Spasmolytic flavonols from Artemisia abrotanum
(1995) In Planta Medica 61(4). p.370-371- Abstract
- Four flavonols with spasmolytic activity have been isolated from a methanol extract of Artemisia abrotanum L. (Asteraceae), as the principles primarily responsible for the smooth muscle relaxing activity of this plant. The flavonols show a dose-dependent relaxing effect on the carbacholine-induced contraction of guinea-pig trachea, the EC50 values for compounds 1-3 are 20-30 mumol/l while compound 4 is less active.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1109352
- author
- Bergendorff, Ola LU and Sterner, Olov LU
- organization
- publishing date
- 1995
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Planta Medica
- volume
- 61
- issue
- 4
- pages
- 370 - 371
- publisher
- Georg Thieme Verlag
- external identifiers
-
- pmid:7480189
- scopus:0029160539
- ISSN
- 0032-0943
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240), Department of Dermatology and Venereology (Lund) (013006000)
- id
- e86e8604-8f0e-4044-8a4e-4e34ddf288c9 (old id 1109352)
- date added to LUP
- 2016-04-01 11:54:20
- date last changed
- 2021-07-25 05:47:07
@article{e86e8604-8f0e-4044-8a4e-4e34ddf288c9, abstract = {{Four flavonols with spasmolytic activity have been isolated from a methanol extract of Artemisia abrotanum L. (Asteraceae), as the principles primarily responsible for the smooth muscle relaxing activity of this plant. The flavonols show a dose-dependent relaxing effect on the carbacholine-induced contraction of guinea-pig trachea, the EC50 values for compounds 1-3 are 20-30 mumol/l while compound 4 is less active.}}, author = {{Bergendorff, Ola and Sterner, Olov}}, issn = {{0032-0943}}, language = {{eng}}, number = {{4}}, pages = {{370--371}}, publisher = {{Georg Thieme Verlag}}, series = {{Planta Medica}}, title = {{Spasmolytic flavonols from Artemisia abrotanum}}, volume = {{61}}, year = {{1995}}, }