Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia
(1995) In Phytochemistry 38(4). p.835-836- Abstract
- S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1109354
- author
- Andersson, Maria ; Bergendorff, Ola LU ; Nielsen, Mogens ; Sterner, Olov LU ; Witt, Robin ; Ai, Jinglu ; Lu, Aiping and Wang, An Min
- organization
- publishing date
- 1995
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Phytochemistry
- volume
- 38
- issue
- 4
- pages
- 835 - 836
- publisher
- Elsevier
- external identifiers
-
- pmid:7766386
- scopus:0029257197
- ISSN
- 0031-9422
- DOI
- 10.1016/0031-9422(94)00771-K
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Organic chemistry (S/LTH) (011001240)
- id
- 77582624-c154-4150-a110-8375a14145b4 (old id 1109354)
- date added to LUP
- 2016-04-01 15:45:22
- date last changed
- 2021-08-08 05:14:19
@article{77582624-c154-4150-a110-8375a14145b4, abstract = {{S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.}}, author = {{Andersson, Maria and Bergendorff, Ola and Nielsen, Mogens and Sterner, Olov and Witt, Robin and Ai, Jinglu and Lu, Aiping and Wang, An Min}}, issn = {{0031-9422}}, language = {{eng}}, number = {{4}}, pages = {{835--836}}, publisher = {{Elsevier}}, series = {{Phytochemistry}}, title = {{Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia}}, url = {{http://dx.doi.org/10.1016/0031-9422(94)00771-K}}, doi = {{10.1016/0031-9422(94)00771-K}}, volume = {{38}}, year = {{1995}}, }