Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions
(1997) In Acta Radiologica 38(6). p.953-960- Abstract
- PURPOSE: To describe the introduction and performance of proton MR spectroscopy (1H-MRS) in the daily routine of a modern standard MR unit. MATERIAL AND METHODS: Over an 8-month period, 52 patients with brain lesions were studied with 1H-MRS, using SE and STEAM sequences for chemical-shift imaging and single-volume spectroscopy. The quality of the spectra was graded from 1 (best) to 3, and the main factors influencing the quality of the spectra were evaluated. RESULTS: Of the measurements: 85% were graded as 1; 12% as 2; and 3% as 3. The main reasons for poor spectral quality were: the unfortunate positioning of the VOI; hemorrhage; and/or postoperative changes within the VOI. Of 40 patients with a final diagnosis: MRS provided an... (More)
- PURPOSE: To describe the introduction and performance of proton MR spectroscopy (1H-MRS) in the daily routine of a modern standard MR unit. MATERIAL AND METHODS: Over an 8-month period, 52 patients with brain lesions were studied with 1H-MRS, using SE and STEAM sequences for chemical-shift imaging and single-volume spectroscopy. The quality of the spectra was graded from 1 (best) to 3, and the main factors influencing the quality of the spectra were evaluated. RESULTS: Of the measurements: 85% were graded as 1; 12% as 2; and 3% as 3. The main reasons for poor spectral quality were: the unfortunate positioning of the VOI; hemorrhage; and/or postoperative changes within the VOI. Of 40 patients with a final diagnosis: MRS provided an increased confidence in MR diagnosis in 18 cases; MRS contributed significantly to preoperative diagnosis in 3 cases; and the spectra were not specific (n = 10) or were difficult to evaluate (n = 9) owing to reduced quality (grade 2 or 3) in 19 cases. CONCLUSION: MRS of the brain can provide a high percentage of interpretable spectra and frequently can increase confidence in the MR diagnosis of brain lesions in clinical routine. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1111623
- author
- Björkman-Burtscher, Isabella LU ; Ståhlberg, Freddy LU and Holtås, Stig LU
- organization
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Radiologica
- volume
- 38
- issue
- 6
- pages
- 953 - 960
- publisher
- SAGE Publications
- external identifiers
-
- pmid:9394648
- scopus:0031278360
- ISSN
- 1600-0455
- language
- English
- LU publication?
- yes
- id
- a7936a38-f4f0-40ce-97d4-68f75a808034 (old id 1111623)
- date added to LUP
- 2016-04-01 16:04:52
- date last changed
- 2022-02-05 05:39:30
@article{a7936a38-f4f0-40ce-97d4-68f75a808034, abstract = {{PURPOSE: To describe the introduction and performance of proton MR spectroscopy (1H-MRS) in the daily routine of a modern standard MR unit. MATERIAL AND METHODS: Over an 8-month period, 52 patients with brain lesions were studied with 1H-MRS, using SE and STEAM sequences for chemical-shift imaging and single-volume spectroscopy. The quality of the spectra was graded from 1 (best) to 3, and the main factors influencing the quality of the spectra were evaluated. RESULTS: Of the measurements: 85% were graded as 1; 12% as 2; and 3% as 3. The main reasons for poor spectral quality were: the unfortunate positioning of the VOI; hemorrhage; and/or postoperative changes within the VOI. Of 40 patients with a final diagnosis: MRS provided an increased confidence in MR diagnosis in 18 cases; MRS contributed significantly to preoperative diagnosis in 3 cases; and the spectra were not specific (n = 10) or were difficult to evaluate (n = 9) owing to reduced quality (grade 2 or 3) in 19 cases. CONCLUSION: MRS of the brain can provide a high percentage of interpretable spectra and frequently can increase confidence in the MR diagnosis of brain lesions in clinical routine.}}, author = {{Björkman-Burtscher, Isabella and Ståhlberg, Freddy and Holtås, Stig}}, issn = {{1600-0455}}, language = {{eng}}, number = {{6}}, pages = {{953--960}}, publisher = {{SAGE Publications}}, series = {{Acta Radiologica}}, title = {{Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions}}, volume = {{38}}, year = {{1997}}, }