Respiratory mechanics after 180 days space mission (EUROMIR'95)
(1998) In Acta Astronautica 42(1-8). p.185-204- Abstract
- The present study reports data on respiratory function of lung and chest wall following the 180 days long European - Russian EuroMir '95 space mission. Data reported refer to two subjects studied before the mission, on day 9 and 175 in flight and on days 1, 10, 12, 27 and 120 after return. In-flight vital capacity (VC) and expiratory reserve volume (ERV) were similar to those in supine posture, namely approximately 5% and approximately 30% less than in sitting posture. On day 1 after return, VC was reduced by approximately 30% in both postures. This reflected a decrease in ERV (approximately 0.5 L) and in IC (inspiratory capacity, approximately 1.7 L) that could be attributed to a marked weakening of the respiratory muscles. Regain of... (More)
- The present study reports data on respiratory function of lung and chest wall following the 180 days long European - Russian EuroMir '95 space mission. Data reported refer to two subjects studied before the mission, on day 9 and 175 in flight and on days 1, 10, 12, 27 and 120 after return. In-flight vital capacity (VC) and expiratory reserve volume (ERV) were similar to those in supine posture, namely approximately 5% and approximately 30% less than in sitting posture. On day 1 after return, VC was reduced by approximately 30% in both postures. This reflected a decrease in ERV (approximately 0.5 L) and in IC (inspiratory capacity, approximately 1.7 L) that could be attributed to a marked weakening of the respiratory muscles. Regain of normal preflight values barely occurred 120 days after return. Post-flight pressure-volume curves of the lung, chest wall and total respiratory system are equal to preflight ones. The pressure-volume curve of the lung in supine posture is displaced to the right relative to sitting posture and shows a lower compliance. As far as the lung in-flight condition resembles that occurring in supine posture, this implies a lower compliance, a greater amount of blood in the pulmonary microvascular bed, a more homogeneous lung perfusion and therefore a greater microvascular filtration rate towards lung interstitium. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1113093
- author
- Venturoli, Daniele LU ; Semino, P ; Negrini, D and Miserocchi, G
- publishing date
- 1998
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Astronautica
- volume
- 42
- issue
- 1-8
- pages
- 185 - 204
- publisher
- Elsevier
- external identifiers
-
- pmid:11541602
- scopus:0031598524
- ISSN
- 0094-5765
- DOI
- 10.1016/S0094-5765(98)00116-7
- language
- English
- LU publication?
- no
- id
- b72d0155-48ef-4e6f-a1af-556d1456da14 (old id 1113093)
- date added to LUP
- 2016-04-01 15:32:16
- date last changed
- 2022-01-28 05:49:06
@article{b72d0155-48ef-4e6f-a1af-556d1456da14,
abstract = {{The present study reports data on respiratory function of lung and chest wall following the 180 days long European - Russian EuroMir '95 space mission. Data reported refer to two subjects studied before the mission, on day 9 and 175 in flight and on days 1, 10, 12, 27 and 120 after return. In-flight vital capacity (VC) and expiratory reserve volume (ERV) were similar to those in supine posture, namely approximately 5% and approximately 30% less than in sitting posture. On day 1 after return, VC was reduced by approximately 30% in both postures. This reflected a decrease in ERV (approximately 0.5 L) and in IC (inspiratory capacity, approximately 1.7 L) that could be attributed to a marked weakening of the respiratory muscles. Regain of normal preflight values barely occurred 120 days after return. Post-flight pressure-volume curves of the lung, chest wall and total respiratory system are equal to preflight ones. The pressure-volume curve of the lung in supine posture is displaced to the right relative to sitting posture and shows a lower compliance. As far as the lung in-flight condition resembles that occurring in supine posture, this implies a lower compliance, a greater amount of blood in the pulmonary microvascular bed, a more homogeneous lung perfusion and therefore a greater microvascular filtration rate towards lung interstitium.}},
author = {{Venturoli, Daniele and Semino, P and Negrini, D and Miserocchi, G}},
issn = {{0094-5765}},
language = {{eng}},
number = {{1-8}},
pages = {{185--204}},
publisher = {{Elsevier}},
series = {{Acta Astronautica}},
title = {{Respiratory mechanics after 180 days space mission (EUROMIR'95)}},
url = {{http://dx.doi.org/10.1016/S0094-5765(98)00116-7}},
doi = {{10.1016/S0094-5765(98)00116-7}},
volume = {{42}},
year = {{1998}},
}