Differential proteinase expression by Pseudomonas aeruginosa derived from chronic leg ulcers
(2001) In Acta Dermato-Venereologica 81(6). p.406-409- Abstract
- Pseudomonas aeruginosa colonizes 20-30% of all venous leg ulcers. Hypothetically, P. aeraginosa could release proteases and cytotoxic substances in the environment of chronic ulcers, thus negatively affecting the wound-healing activity in this patient group. Here we show that P. aeruginosa isolates from leg ulcers exhibit a highly variable expression of the proteinases elastase and alkaline proteinase. We propose that bacterial phenotype should be taken into account in future studies on the clinical outcome of leg ulcers colonized by P. aeruginosa.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1121494
- author
- Schmidtchen, Artur LU ; Wolff, Helene and Hansson, Carita
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Bacteria, Virulence, Factor, Wound, Healing
- in
- Acta Dermato-Venereologica
- volume
- 81
- issue
- 6
- pages
- 406 - 409
- publisher
- Medical Journals Limited
- external identifiers
-
- pmid:11859942
- scopus:0035701613
- ISSN
- 1651-2057
- DOI
- 10.1080/000155501317208336
- language
- English
- LU publication?
- yes
- id
- f9b7f78e-ed57-4004-b4eb-03361c2391ee (old id 1121494)
- date added to LUP
- 2016-04-01 17:09:44
- date last changed
- 2022-01-29 00:44:43
@article{f9b7f78e-ed57-4004-b4eb-03361c2391ee, abstract = {{Pseudomonas aeruginosa colonizes 20-30% of all venous leg ulcers. Hypothetically, P. aeraginosa could release proteases and cytotoxic substances in the environment of chronic ulcers, thus negatively affecting the wound-healing activity in this patient group. Here we show that P. aeruginosa isolates from leg ulcers exhibit a highly variable expression of the proteinases elastase and alkaline proteinase. We propose that bacterial phenotype should be taken into account in future studies on the clinical outcome of leg ulcers colonized by P. aeruginosa.}}, author = {{Schmidtchen, Artur and Wolff, Helene and Hansson, Carita}}, issn = {{1651-2057}}, keywords = {{Bacteria; Virulence; Factor; Wound; Healing}}, language = {{eng}}, number = {{6}}, pages = {{406--409}}, publisher = {{Medical Journals Limited}}, series = {{Acta Dermato-Venereologica}}, title = {{Differential proteinase expression by Pseudomonas aeruginosa derived from chronic leg ulcers}}, url = {{http://dx.doi.org/10.1080/000155501317208336}}, doi = {{10.1080/000155501317208336}}, volume = {{81}}, year = {{2001}}, }