Influence of factor V Leiden on the development of neovascularisation secondary to central retinal vein occlusion.
(2003) In British Journal of Ophthalmology 87(3). p.305-306- Abstract
- Aims: To investigate if the presence of factor V Leiden has an influence on the prognosis in central retinal vein occlusion (CRVO).
Methods: 166 patients with CRVO were studied retrospectively. They were tested for factor V Leiden using DNA analysis. The presence of the mutation was studied in correlation with the development of neovascular complications 1 year after the thrombotic event.
Results: 56 of 166 patients (34%) developed neovascular complications after 1 year. In the patients who had the studied mutation 11 of 20 (55%) had developed neovascular complications after 1 year, compared to 45 of 146 patients (31%) in the group without factor V Leiden (p=0.04).
Conclusion: The... (More) - Aims: To investigate if the presence of factor V Leiden has an influence on the prognosis in central retinal vein occlusion (CRVO).
Methods: 166 patients with CRVO were studied retrospectively. They were tested for factor V Leiden using DNA analysis. The presence of the mutation was studied in correlation with the development of neovascular complications 1 year after the thrombotic event.
Results: 56 of 166 patients (34%) developed neovascular complications after 1 year. In the patients who had the studied mutation 11 of 20 (55%) had developed neovascular complications after 1 year, compared to 45 of 146 patients (31%) in the group without factor V Leiden (p=0.04).
Conclusion: The presence of factor V Leiden seems to enhance the risk of developing neovascular complications in CRVO. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/112250
- author
- Lindberg, Charlotte LU ; Hillarp, Andreas LU and Larsson, Jörgen LU
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- British Journal of Ophthalmology
- volume
- 87
- issue
- 3
- pages
- 305 - 306
- publisher
- BMJ Publishing Group
- external identifiers
-
- pmid:12598443
- wos:000181368500015
- scopus:0037340035
- ISSN
- 1468-2079
- DOI
- 10.1136/bjo.87.3.305
- language
- English
- LU publication?
- yes
- id
- c821543c-79e2-4cc8-96c7-3f5a8f69846f (old id 112250)
- alternative location
- http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=12598443&dopt=Abstract
- date added to LUP
- 2016-04-01 15:53:29
- date last changed
- 2022-01-28 07:49:37
@article{c821543c-79e2-4cc8-96c7-3f5a8f69846f,
abstract = {{Aims: To investigate if the presence of factor V Leiden has an influence on the prognosis in central retinal vein occlusion (CRVO). <br/><br>
<br/><br>
Methods: 166 patients with CRVO were studied retrospectively. They were tested for factor V Leiden using DNA analysis. The presence of the mutation was studied in correlation with the development of neovascular complications 1 year after the thrombotic event. <br/><br>
<br/><br>
Results: 56 of 166 patients (34%) developed neovascular complications after 1 year. In the patients who had the studied mutation 11 of 20 (55%) had developed neovascular complications after 1 year, compared to 45 of 146 patients (31%) in the group without factor V Leiden (p=0.04). <br/><br>
<br/><br>
Conclusion: The presence of factor V Leiden seems to enhance the risk of developing neovascular complications in CRVO.}},
author = {{Lindberg, Charlotte and Hillarp, Andreas and Larsson, Jörgen}},
issn = {{1468-2079}},
language = {{eng}},
number = {{3}},
pages = {{305--306}},
publisher = {{BMJ Publishing Group}},
series = {{British Journal of Ophthalmology}},
title = {{Influence of factor V Leiden on the development of neovascularisation secondary to central retinal vein occlusion.}},
url = {{https://lup.lub.lu.se/search/files/4504492/623704.pdf}},
doi = {{10.1136/bjo.87.3.305}},
volume = {{87}},
year = {{2003}},
}