DNA and cell cycle analysis as prognostic indicators in breast tumors revisited
(2001) In Clinics in Laboratory Medicine 21(4). p.875-895- Abstract
- Both DNA ploidy and S-phase ploidy are promising prognostic factors for node-negative breast cancer patients. Based largely on the analysis of one large study, much of the reported problems with these factors have been caused by some unappreciated complexities in categorizing DNA ploidy into low- and high-risk groups and the lack of some necessary adjustments to eliminate unwanted correlations between DNA S-phase and ploidy. When both DNA ploidy and S-phase are compensated properly, they become independent prognostic markers, forming a powerful prognostic model.
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https://lup.lub.lu.se/record/1123130
- author
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinics in Laboratory Medicine
- volume
- 21
- issue
- 4
- pages
- 875 - 895
- publisher
- W.B. Saunders
- external identifiers
-
- pmid:11770293
- scopus:0035206075
- ISSN
- 0272-2712
- language
- English
- LU publication?
- yes
- id
- b4f605f6-9f53-4443-a2d4-6b7e079d46de (old id 1123130)
- date added to LUP
- 2016-04-01 15:34:35
- date last changed
- 2022-01-28 06:00:05
@article{b4f605f6-9f53-4443-a2d4-6b7e079d46de, abstract = {{Both DNA ploidy and S-phase ploidy are promising prognostic factors for node-negative breast cancer patients. Based largely on the analysis of one large study, much of the reported problems with these factors have been caused by some unappreciated complexities in categorizing DNA ploidy into low- and high-risk groups and the lack of some necessary adjustments to eliminate unwanted correlations between DNA S-phase and ploidy. When both DNA ploidy and S-phase are compensated properly, they become independent prognostic markers, forming a powerful prognostic model.}}, author = {{Bagwell, C B and Clark, G M and Spyratos, F and Chassevent, A and Bendahl, Pär-Ola and Stal, O and Killander, D and Jourdan, M L and Romain, S and Hunsberger, B and Wright, S and Baldetorp, Bo}}, issn = {{0272-2712}}, language = {{eng}}, number = {{4}}, pages = {{875--895}}, publisher = {{W.B. Saunders}}, series = {{Clinics in Laboratory Medicine}}, title = {{DNA and cell cycle analysis as prognostic indicators in breast tumors revisited}}, volume = {{21}}, year = {{2001}}, }