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The activity in the CNS catecholaminergic systems covaries with thyroid hormone metabolism in humans

Yhede, R ; Blennow, Kaj LU ; Forsman, A and Anckarsäter, Henrik LU (2003) In Journal of Neural Transmission 110(12). p.1369-1373
Abstract
Do the CNS monoaminergic (MA) systems regulate thyroid hormone metabolism in humans? In 23 unmedicated, male, violent offenders without signs of thyroid disease, we found positive correlations between the catecholaminergic CSF metabolites HVA and MHPG and the peripheral T3/T4 ratio (rho=0.55, p=0.010 and 0.51, p=0.018), indicating that increased activity in the brain MA systems, especially the dopaminergic, is associated with increased peripheral thyroid hormone activity.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Dopamine, serotonin, thyroxine, triiodothyroxine
in
Journal of Neural Transmission
volume
110
issue
12
pages
1369 - 1373
publisher
Springer
external identifiers
  • pmid:14666409
  • scopus:0347991770
ISSN
0300-9564
DOI
10.1007/s00702-003-0073-z
language
English
LU publication?
yes
id
1108c1f5-6acf-4280-b1c6-8f25cfb41d25 (old id 1126641)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/14666409
http://link.springer.com/article/10.1007%2Fs00702-003-0073-z
date added to LUP
2016-04-01 16:27:03
date last changed
2022-01-28 19:50:23
@article{1108c1f5-6acf-4280-b1c6-8f25cfb41d25,
  abstract     = {{Do the CNS monoaminergic (MA) systems regulate thyroid hormone metabolism in humans? In 23 unmedicated, male, violent offenders without signs of thyroid disease, we found positive correlations between the catecholaminergic CSF metabolites HVA and MHPG and the peripheral T3/T4 ratio (rho=0.55, p=0.010 and 0.51, p=0.018), indicating that increased activity in the brain MA systems, especially the dopaminergic, is associated with increased peripheral thyroid hormone activity.}},
  author       = {{Yhede, R and Blennow, Kaj and Forsman, A and Anckarsäter, Henrik}},
  issn         = {{0300-9564}},
  keywords     = {{Dopamine; serotonin; thyroxine; triiodothyroxine}},
  language     = {{eng}},
  number       = {{12}},
  pages        = {{1369--1373}},
  publisher    = {{Springer}},
  series       = {{Journal of Neural Transmission}},
  title        = {{The activity in the CNS catecholaminergic systems covaries with thyroid hormone metabolism in humans}},
  url          = {{http://dx.doi.org/10.1007/s00702-003-0073-z}},
  doi          = {{10.1007/s00702-003-0073-z}},
  volume       = {{110}},
  year         = {{2003}},
}