A controlled study of tryptophan and cortisol in violent offenders
(2004) In Journal of Neural Transmission 111(12). p.1605-1610- Abstract
- Changes in the metabolism of tryptophan, other amino acids, and steroid hormones have been implicated in aggression. We compared tryptophan, competing long amino acids (CAAs), and cortisol in serum (S) and CSF in 22 violent offenders and 15 healthy controls. Offenders had significantly increased S-L-tryptophan, S-free tryptophan, S-CAAs, S-cortisol and CSF-cortisol, indicating abnormal neurophysiological processes. Larger studies on the interplay between violence, serotonin precursors, and stress hormones need to integrate personality traits, life situations, and physiological adaptation.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1129366
- author
- Söderström, Henrik LU ; Blennow, Kaj LU ; Forsman, A ; Liesivuori, J ; Pennanen, S and Tiihonen, J
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Forensic psychiatry, violent behavior, serotonin, cortisol
- in
- Journal of Neural Transmission
- volume
- 111
- issue
- 12
- pages
- 1605 - 1610
- publisher
- Springer
- external identifiers
-
- pmid:15565494
- scopus:11244267199
- ISSN
- 0300-9564
- DOI
- 10.1007/s00702-004-0219-7
- language
- English
- LU publication?
- no
- id
- 5f4c39a1-e0c1-4caa-9b63-2beb42ca87bd (old id 1129366)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/15565494
- http://link.springer.com/article/10.1007%2Fs00702-004-0219-7
- date added to LUP
- 2016-04-01 16:27:31
- date last changed
- 2022-01-28 19:50:29
@article{5f4c39a1-e0c1-4caa-9b63-2beb42ca87bd, abstract = {{Changes in the metabolism of tryptophan, other amino acids, and steroid hormones have been implicated in aggression. We compared tryptophan, competing long amino acids (CAAs), and cortisol in serum (S) and CSF in 22 violent offenders and 15 healthy controls. Offenders had significantly increased S-L-tryptophan, S-free tryptophan, S-CAAs, S-cortisol and CSF-cortisol, indicating abnormal neurophysiological processes. Larger studies on the interplay between violence, serotonin precursors, and stress hormones need to integrate personality traits, life situations, and physiological adaptation.}}, author = {{Söderström, Henrik and Blennow, Kaj and Forsman, A and Liesivuori, J and Pennanen, S and Tiihonen, J}}, issn = {{0300-9564}}, keywords = {{Forensic psychiatry; violent behavior; serotonin; cortisol}}, language = {{eng}}, number = {{12}}, pages = {{1605--1610}}, publisher = {{Springer}}, series = {{Journal of Neural Transmission}}, title = {{A controlled study of tryptophan and cortisol in violent offenders}}, url = {{http://dx.doi.org/10.1007/s00702-004-0219-7}}, doi = {{10.1007/s00702-004-0219-7}}, volume = {{111}}, year = {{2004}}, }