Risk of developing diabetes is inversely related to lung function: a population-based cohort study.
(2002) In Diabetic Medicine 19(2). p.167-170- Abstract
- AimTo investigate whether reduced lung function is a risk factor for developing diabetes.
MethodsNon-diabetic men (n = 382) from the population-based cohort 'Men Born in 1914' were examined with spirometry at age 55 years. The cohort was re-examined at 68 years. Diabetes and fasting plasma glucose at follow-up were studied in relation to vital capacity (VC) and forced expiratory volume (FEV1.0) at baseline.
ResultsFifteen men developed diabetes during the follow-up. The percentage with diabetes in the 1st, 2nd, 3rd and top quartile of vital capacity were 7%, 5%, 2%, and 1%, respectively (P for trend = 0.01). Fasting glucose (log transformed, mmol/l) at follow-up was 1.63 ± 0.16, 1.62 ± 0.18, 1.61 ±... (More) - AimTo investigate whether reduced lung function is a risk factor for developing diabetes.
MethodsNon-diabetic men (n = 382) from the population-based cohort 'Men Born in 1914' were examined with spirometry at age 55 years. The cohort was re-examined at 68 years. Diabetes and fasting plasma glucose at follow-up were studied in relation to vital capacity (VC) and forced expiratory volume (FEV1.0) at baseline.
ResultsFifteen men developed diabetes during the follow-up. The percentage with diabetes in the 1st, 2nd, 3rd and top quartile of vital capacity were 7%, 5%, 2%, and 1%, respectively (P for trend = 0.01). Fasting glucose (log transformed, mmol/l) at follow-up was 1.63 ± 0.16, 1.62 ± 0.18, 1.61 ± 0.11 and 1.60 ± 0.11, respectively (P for trend = 0.11). The longitudinal associations between VC and diabetes (P = 0.001) and log glucose (P = 0.036) were significant after adjustments for several potential confounders. FEV1.0 at baseline showed similar associations with diabetes at follow-up.
ConclusionsThe risk of developing diabetes is inversely associated with pulmonary function among middle-aged men. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/115537
- author
- Engström, Gunnar LU and Janzon, Lars LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Forced Expiratory Volume: physiology, Blood Glucose: metabolism, Blood Pressure, Body Mass Index, Cohort Studies, Diabetes Mellitus: epidemiology, Exercise, Human, Longitudinal Studies, Male, Middle Age, Respiratory Function Tests, Risk Factors, Smoking, Support, Non-U.S. Gov't, Sweden: epidemiology, Vital Capacity: physiology
- in
- Diabetic Medicine
- volume
- 19
- issue
- 2
- pages
- 167 - 170
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000174576300014
- pmid:11874435
- scopus:0036125054
- ISSN
- 1464-5491
- DOI
- 10.1046/j.1464-5491.2002.00652.x
- language
- English
- LU publication?
- yes
- id
- 0e0d87f6-98cd-4d62-be85-3a2d97190156 (old id 115537)
- date added to LUP
- 2016-04-01 16:46:18
- date last changed
- 2022-01-28 22:01:23
@article{0e0d87f6-98cd-4d62-be85-3a2d97190156,
abstract = {{AimTo investigate whether reduced lung function is a risk factor for developing diabetes.<br/><br>
<br/><br>
MethodsNon-diabetic men (n = 382) from the population-based cohort 'Men Born in 1914' were examined with spirometry at age 55 years. The cohort was re-examined at 68 years. Diabetes and fasting plasma glucose at follow-up were studied in relation to vital capacity (VC) and forced expiratory volume (FEV1.0) at baseline.<br/><br>
<br/><br>
ResultsFifteen men developed diabetes during the follow-up. The percentage with diabetes in the 1st, 2nd, 3rd and top quartile of vital capacity were 7%, 5%, 2%, and 1%, respectively (P for trend = 0.01). Fasting glucose (log transformed, mmol/l) at follow-up was 1.63 ± 0.16, 1.62 ± 0.18, 1.61 ± 0.11 and 1.60 ± 0.11, respectively (P for trend = 0.11). The longitudinal associations between VC and diabetes (P = 0.001) and log glucose (P = 0.036) were significant after adjustments for several potential confounders. FEV1.0 at baseline showed similar associations with diabetes at follow-up.<br/><br>
<br/><br>
ConclusionsThe risk of developing diabetes is inversely associated with pulmonary function among middle-aged men.}},
author = {{Engström, Gunnar and Janzon, Lars}},
issn = {{1464-5491}},
keywords = {{Forced Expiratory Volume: physiology; Blood Glucose: metabolism; Blood Pressure; Body Mass Index; Cohort Studies; Diabetes Mellitus: epidemiology; Exercise; Human; Longitudinal Studies; Male; Middle Age; Respiratory Function Tests; Risk Factors; Smoking; Support; Non-U.S. Gov't; Sweden: epidemiology; Vital Capacity: physiology}},
language = {{eng}},
number = {{2}},
pages = {{167--170}},
publisher = {{Wiley-Blackwell}},
series = {{Diabetic Medicine}},
title = {{Risk of developing diabetes is inversely related to lung function: a population-based cohort study.}},
url = {{https://lup.lub.lu.se/search/files/4775551/623802.pdf}},
doi = {{10.1046/j.1464-5491.2002.00652.x}},
volume = {{19}},
year = {{2002}},
}