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Water uptake and release from iodine-containing bone cement.

Kjellson, Fred LU ; Brudeli, B. ; McCarthy, Ian LU and Lidgren, Lars LU (2004) In Journal of Biomedical Materials Research. Part A 71(2). p.292-298
Abstract
Water uptake and release characteristics of PMMA cement containing the water-soluble contrast media iohexol or iodixanol have been investigated. The water uptake study revealed that iohexol had the highest uptake of water (3.7%) and that iodixanol had an uptake close to that of Palacos(R) R (2.3% and 1.9%). The curves obtained showed the materials to follow classic diffusion theory, with an initial linearity with respect to t(1/2) making it possible to calculate the diffusion coefficients. This showed iohexol to have the lowest diffusion coefficient, Palacos(R) R the highest, and iodixanol close to that of Palacos(R) R. The release study showed that more iohexol than iodixanol was released from the bone cement; the long-term release was... (More)
Water uptake and release characteristics of PMMA cement containing the water-soluble contrast media iohexol or iodixanol have been investigated. The water uptake study revealed that iohexol had the highest uptake of water (3.7%) and that iodixanol had an uptake close to that of Palacos(R) R (2.3% and 1.9%). The curves obtained showed the materials to follow classic diffusion theory, with an initial linearity with respect to t(1/2) making it possible to calculate the diffusion coefficients. This showed iohexol to have the lowest diffusion coefficient, Palacos(R) R the highest, and iodixanol close to that of Palacos(R) R. The release study showed that more iohexol than iodixanol was released from the bone cement; the long-term release was above 25 mug/ml, for iohexol compared to slightly above 10 mug/mL for iodixanol. A muCT investigation showed that the risk of developing an observable radiolucent zone is negligible. (C) 2004 Wiley Periodicals, Inc. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
water uptake, water, release, poly(methyl methacrylate), absorption characteristics
in
Journal of Biomedical Materials Research. Part A
volume
71
issue
2
pages
292 - 298
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:15386486
  • wos:000224419000013
  • scopus:5444232124
ISSN
1552-4965
DOI
10.1002/jbm.a.30162
language
English
LU publication?
yes
id
ca77edb8-9923-43d0-80c7-0181cd633ccf (old id 127220)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15386486&dopt=Abstract
date added to LUP
2016-04-01 12:25:42
date last changed
2022-01-27 03:38:27
@article{ca77edb8-9923-43d0-80c7-0181cd633ccf,
  abstract     = {{Water uptake and release characteristics of PMMA cement containing the water-soluble contrast media iohexol or iodixanol have been investigated. The water uptake study revealed that iohexol had the highest uptake of water (3.7%) and that iodixanol had an uptake close to that of Palacos(R) R (2.3% and 1.9%). The curves obtained showed the materials to follow classic diffusion theory, with an initial linearity with respect to t(1/2) making it possible to calculate the diffusion coefficients. This showed iohexol to have the lowest diffusion coefficient, Palacos(R) R the highest, and iodixanol close to that of Palacos(R) R. The release study showed that more iohexol than iodixanol was released from the bone cement; the long-term release was above 25 mug/ml, for iohexol compared to slightly above 10 mug/mL for iodixanol. A muCT investigation showed that the risk of developing an observable radiolucent zone is negligible. (C) 2004 Wiley Periodicals, Inc.}},
  author       = {{Kjellson, Fred and Brudeli, B. and McCarthy, Ian and Lidgren, Lars}},
  issn         = {{1552-4965}},
  keywords     = {{water uptake; water; release; poly(methyl methacrylate); absorption characteristics}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{292--298}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Journal of Biomedical Materials Research. Part A}},
  title        = {{Water uptake and release from iodine-containing bone cement.}},
  url          = {{http://dx.doi.org/10.1002/jbm.a.30162}},
  doi          = {{10.1002/jbm.a.30162}},
  volume       = {{71}},
  year         = {{2004}},
}