Quantitative polar representation of left ventricular myocardial perfusion, function and viability using SPECT and cardiac magnetic resonance: initial results.
(2005) In Clinical Physiology and Functional Imaging 25(4). p.215-222- Abstract
- Background: The clinical management of patients with coronary artery disease (CAD) often involves a complex assessment of the extent and severity of changes in left ventricular (LV) myocardial perfusion, function and viability. We aimed to explore the feasibility of integrative quantitative representation of LV perfusion, function and viability in adjacent polar plots. In order to assess the clinical usefulness of the quantitative methods, we also explored the relationship and determined the agreement between visual scoring and quantitative measurement of regional perfusion and function.
Methods: Ten patients with CAD underwent rest and stress 99mTc-tetrofosmin single photon emission computed tomography (SPECT) and... (More) - Background: The clinical management of patients with coronary artery disease (CAD) often involves a complex assessment of the extent and severity of changes in left ventricular (LV) myocardial perfusion, function and viability. We aimed to explore the feasibility of integrative quantitative representation of LV perfusion, function and viability in adjacent polar plots. In order to assess the clinical usefulness of the quantitative methods, we also explored the relationship and determined the agreement between visual scoring and quantitative measurement of regional perfusion and function.
Methods: Ten patients with CAD underwent rest and stress 99mTc-tetrofosmin single photon emission computed tomography (SPECT) and cardiac magnetic resonance (CMR) imaging. Software was developed in-house for generating polar plots from semi-automatic quantification of rest and stress perfusion from SPECT, function from cine CMR and viability from delayed contrast enhancement (DE) CMR. The agreement between visual assessment and quantification of both perfusion and function was tested by Kendall's coefficient of concordance (W).
Results: Polar plots were created using quantitative data from the semi-automatic analysis of perfusion, function and viability. Kendall's W for agreement between quantitative measurement and visual scoring was 1·0 (P<0·001) for perfusion and 0·85 (P<0·001) for function.
Conclusions: Side-by-side quantitative polar representation of LV perfusion, function and viability is feasible and may aid in the complex assessment of these parameters. The agreement between quantitative measurement and visual scoring was very good for both perfusion and function. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/139848
- author
- Cain, Peter LU ; Ugander, Martin LU ; Palmer, John LU ; Carlsson, Marcus LU ; Heiberg, Einar LU and Arheden, Håkan LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical Physiology and Functional Imaging
- volume
- 25
- issue
- 4
- pages
- 215 - 222
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000229956800005
- pmid:15972023
- scopus:21644465657
- pmid:15972023
- ISSN
- 1475-0961
- DOI
- 10.1111/j.1475-097X.2005.00618.x
- language
- English
- LU publication?
- yes
- id
- 3c745cb1-e64b-47da-bda6-edd42b808942 (old id 139848)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15972023&query_hl=140
- date added to LUP
- 2016-04-01 12:31:38
- date last changed
- 2022-01-27 06:16:29
@article{3c745cb1-e64b-47da-bda6-edd42b808942,
abstract = {{Background: The clinical management of patients with coronary artery disease (CAD) often involves a complex assessment of the extent and severity of changes in left ventricular (LV) myocardial perfusion, function and viability. We aimed to explore the feasibility of integrative quantitative representation of LV perfusion, function and viability in adjacent polar plots. In order to assess the clinical usefulness of the quantitative methods, we also explored the relationship and determined the agreement between visual scoring and quantitative measurement of regional perfusion and function.<br/><br>
<br/><br>
Methods: Ten patients with CAD underwent rest and stress 99mTc-tetrofosmin single photon emission computed tomography (SPECT) and cardiac magnetic resonance (CMR) imaging. Software was developed in-house for generating polar plots from semi-automatic quantification of rest and stress perfusion from SPECT, function from cine CMR and viability from delayed contrast enhancement (DE) CMR. The agreement between visual assessment and quantification of both perfusion and function was tested by Kendall's coefficient of concordance (W).<br/><br>
<br/><br>
Results: Polar plots were created using quantitative data from the semi-automatic analysis of perfusion, function and viability. Kendall's W for agreement between quantitative measurement and visual scoring was 1·0 (P<0·001) for perfusion and 0·85 (P<0·001) for function.<br/><br>
<br/><br>
Conclusions: Side-by-side quantitative polar representation of LV perfusion, function and viability is feasible and may aid in the complex assessment of these parameters. The agreement between quantitative measurement and visual scoring was very good for both perfusion and function.}},
author = {{Cain, Peter and Ugander, Martin and Palmer, John and Carlsson, Marcus and Heiberg, Einar and Arheden, Håkan}},
issn = {{1475-0961}},
language = {{eng}},
number = {{4}},
pages = {{215--222}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Clinical Physiology and Functional Imaging}},
title = {{Quantitative polar representation of left ventricular myocardial perfusion, function and viability using SPECT and cardiac magnetic resonance: initial results.}},
url = {{https://lup.lub.lu.se/search/files/2959307/624743.pdf}},
doi = {{10.1111/j.1475-097X.2005.00618.x}},
volume = {{25}},
year = {{2005}},
}