Report of the Third International Workshop on Molecular Blood Group Genotyping
Daniels, G. ; van der Schoot, C. E. ; Gassner, C. and Olsson, Martin L LU
(2009)
In Vox Sanguinis
96(4).
p.337-343
- Abstract
- The Third International Society of Blood Transfusion Workshop on Molecular Blood Group Genotyping was held in 2008, with a feedback meeting at the International Society of Blood Transfusion Congress in Macao SAR, China. Thirty-three laboratories participated, eight less than in 2006. Six samples were distributed: sample 1 representing DNA from a sample referred because of abnormal serological results in D testing; samples 2 and 3 from transfusion-dependent patients for testing for all clinically important polymorphisms; sample 4 a mixture of two DNA samples designed to simulate a chimera, referred because of abnormal serological results in donor testing; and samples 5 and 6 plasma samples from RhD-negative pregnant women, for fetal RhD... (More)
- The Third International Society of Blood Transfusion Workshop on Molecular Blood Group Genotyping was held in 2008, with a feedback meeting at the International Society of Blood Transfusion Congress in Macao SAR, China. Thirty-three laboratories participated, eight less than in 2006. Six samples were distributed: sample 1 representing DNA from a sample referred because of abnormal serological results in D testing; samples 2 and 3 from transfusion-dependent patients for testing for all clinically important polymorphisms; sample 4 a mixture of two DNA samples designed to simulate a chimera, referred because of abnormal serological results in donor testing; and samples 5 and 6 plasma samples from RhD-negative pregnant women, for fetal RhD testing (only tested by 17 laboratories). For samples 1-3, 24 of 33 laboratories obtained completely correct results. For sample 4, the ability to detect the minority DNA population was partly dependent on method. Of the 17 laboratories that received samples 5 and 6, 13 reported correct results on both samples. Overall a small improvement from previous workshops was noted, but there is still room for improvement. The main conclusion for the 2006 workshop can be reiterated: with greater care and attention to detail, very high standards could be set for molecular blood group genotyping. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1399659
- author
- Daniels, G.
; van der Schoot, C. E.
; Gassner, C.
and Olsson, Martin L
LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Rh, molecular genetics, blood groups, fetal genotyping
- in
- Vox Sanguinis
- volume
- 96
- issue
- 4
- pages
- 337 - 343
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000265190000010
- scopus:59649096216
- pmid:19215623
- ISSN
- 1423-0410
- DOI
- 10.1111/j.1423-0410.2009.01165.x
- language
- English
- LU publication?
- yes
- id
- c63c770c-d2ed-4b08-adf6-0cdc7156d76f (old id 1399659)
- date added to LUP
- 2016-04-01 13:57:27
- date last changed
- 2022-01-27 22:00:34
@article{c63c770c-d2ed-4b08-adf6-0cdc7156d76f,
abstract = {{The Third International Society of Blood Transfusion Workshop on Molecular Blood Group Genotyping was held in 2008, with a feedback meeting at the International Society of Blood Transfusion Congress in Macao SAR, China. Thirty-three laboratories participated, eight less than in 2006. Six samples were distributed: sample 1 representing DNA from a sample referred because of abnormal serological results in D testing; samples 2 and 3 from transfusion-dependent patients for testing for all clinically important polymorphisms; sample 4 a mixture of two DNA samples designed to simulate a chimera, referred because of abnormal serological results in donor testing; and samples 5 and 6 plasma samples from RhD-negative pregnant women, for fetal RhD testing (only tested by 17 laboratories). For samples 1-3, 24 of 33 laboratories obtained completely correct results. For sample 4, the ability to detect the minority DNA population was partly dependent on method. Of the 17 laboratories that received samples 5 and 6, 13 reported correct results on both samples. Overall a small improvement from previous workshops was noted, but there is still room for improvement. The main conclusion for the 2006 workshop can be reiterated: with greater care and attention to detail, very high standards could be set for molecular blood group genotyping.}},
author = {{Daniels, G. and van der Schoot, C. E. and Gassner, C. and Olsson, Martin L}},
issn = {{1423-0410}},
keywords = {{Rh; molecular genetics; blood groups; fetal genotyping}},
language = {{eng}},
number = {{4}},
pages = {{337--343}},
publisher = {{Wiley-Blackwell}},
series = {{Vox Sanguinis}},
title = {{Report of the Third International Workshop on Molecular Blood Group Genotyping}},
url = {{http://dx.doi.org/10.1111/j.1423-0410.2009.01165.x}},
doi = {{10.1111/j.1423-0410.2009.01165.x}},
volume = {{96}},
year = {{2009}},
}