Structural changes in the developing retina maintained in vitro.
Johansson, Kjell LU and Ehinger, Berndt LU
(2005)
In Vision Research
45(25-26).
p.3235-3243
- Abstract
- The present study examined the emergence of structural remodeling in explanted neonatal rat retina. Immunohistochemical analysis demonstrated signs of glial and neuronal remodeling after I I days in vitro and included the activation of Muller cells, the formation of ectopic neuropil areas and sprouting of photoreceptor terminals. We also observed that cholinergic and GABA-ergic amacrine cells displayed signs of disorganized laminations. These results demonstrate that retinal culturing initiates structural changes that show morphological similarities to glial and neuronal remodeling identified in retinitis pigmentosa retinas and experimentally detached retinas.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/142104
- author
- Johansson, Kjell
LU
and Ehinger, Berndt
LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Muller cells, photoreceptor sprouting, in vitro, retina, remodeling
- in
- Vision Research
- volume
- 45
- issue
- 25-26
- pages
- 3235 - 3243
- publisher
- Elsevier
- external identifiers
-
- wos:000233350000014
- pmid:16024061
- scopus:27444438653
- ISSN
- 1878-5646
- DOI
- 10.1016/j.visres.2005.05.022
- language
- English
- LU publication?
- yes
- id
- 506cd131-8bd7-45b1-a46b-ecd34404f9c3 (old id 142104)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16024061&dopt=Abstract
- date added to LUP
- 2016-04-01 12:10:08
- date last changed
- 2022-01-26 23:47:29
@article{506cd131-8bd7-45b1-a46b-ecd34404f9c3,
abstract = {{The present study examined the emergence of structural remodeling in explanted neonatal rat retina. Immunohistochemical analysis demonstrated signs of glial and neuronal remodeling after I I days in vitro and included the activation of Muller cells, the formation of ectopic neuropil areas and sprouting of photoreceptor terminals. We also observed that cholinergic and GABA-ergic amacrine cells displayed signs of disorganized laminations. These results demonstrate that retinal culturing initiates structural changes that show morphological similarities to glial and neuronal remodeling identified in retinitis pigmentosa retinas and experimentally detached retinas.}},
author = {{Johansson, Kjell and Ehinger, Berndt}},
issn = {{1878-5646}},
keywords = {{Muller cells; photoreceptor sprouting; in vitro; retina; remodeling}},
language = {{eng}},
number = {{25-26}},
pages = {{3235--3243}},
publisher = {{Elsevier}},
series = {{Vision Research}},
title = {{Structural changes in the developing retina maintained in vitro.}},
url = {{https://lup.lub.lu.se/search/files/2810276/624806.pdf}},
doi = {{10.1016/j.visres.2005.05.022}},
volume = {{45}},
year = {{2005}},
}