Polymorphisms in the protein C inhibitor gene in in vitro fertilization failure.
(2010) In Fertility and Sterility 93(1). p.277-279- Abstract
- The aim of this study was to determine whether total fertilization failure in human IVF can be partially explained by alterations in the gene that codes for protein C inhibitor. Forty-six men had IVF total fertilization failure and 51 controls with normal fertilization were screened for mutations in the protein C inhibitor gene by direct sequencing. The main finding was that in men involved in total fertilization failure, a heterozygous adenosine/guanine (A/G) base combination in position 1389 (rs2069990) (exon 6) in the protein C inhibitor gene was significantly more common compared with controls (10.9% vs. 0).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1483337
- author
- Bungum, Mona LU ; Giwercman, Aleksander LU ; Bungum, Leif LU ; Humaidan, Peter ; Rastkhani, Hamideh LU and Giwercman, Yvonne LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Fertility and Sterility
- volume
- 93
- issue
- 1
- pages
- 277 - 279
- publisher
- Elsevier
- external identifiers
-
- wos:000273601200041
- pmid:19765701
- scopus:72749110925
- ISSN
- 1556-5653
- DOI
- 10.1016/j.fertnstert.2009.07.984
- language
- English
- LU publication?
- yes
- id
- be7405c5-81c7-4024-9c2e-6a41c0bd06de (old id 1483337)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19765701?dopt=Abstract
- date added to LUP
- 2016-04-01 09:49:27
- date last changed
- 2022-01-25 17:01:27
@article{be7405c5-81c7-4024-9c2e-6a41c0bd06de, abstract = {{The aim of this study was to determine whether total fertilization failure in human IVF can be partially explained by alterations in the gene that codes for protein C inhibitor. Forty-six men had IVF total fertilization failure and 51 controls with normal fertilization were screened for mutations in the protein C inhibitor gene by direct sequencing. The main finding was that in men involved in total fertilization failure, a heterozygous adenosine/guanine (A/G) base combination in position 1389 (rs2069990) (exon 6) in the protein C inhibitor gene was significantly more common compared with controls (10.9% vs. 0).}}, author = {{Bungum, Mona and Giwercman, Aleksander and Bungum, Leif and Humaidan, Peter and Rastkhani, Hamideh and Giwercman, Yvonne}}, issn = {{1556-5653}}, language = {{eng}}, number = {{1}}, pages = {{277--279}}, publisher = {{Elsevier}}, series = {{Fertility and Sterility}}, title = {{Polymorphisms in the protein C inhibitor gene in in vitro fertilization failure.}}, url = {{http://dx.doi.org/10.1016/j.fertnstert.2009.07.984}}, doi = {{10.1016/j.fertnstert.2009.07.984}}, volume = {{93}}, year = {{2010}}, }