Nanowire Biocompatibility in the Brain - Looking for a Needle in a 3D Stack.
(2009) In Nano Letters 9(12). p.4184-4190- Abstract
- We investigated the brain-tissue response to nanowire implantations in the rat striatum after 1, 6, and 12 weeks using immunohistochemistry. The nanowires could be visualized in the scar by confocal microscopy (through the scattered laser light). For the nanowire-implanted animals, there is a significant astrocyte response at week 1 compared to controls. The nanowires are phagocytized by ED1 positive microglia, and some of them are degraded and/or transported away from the brain.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1500121
- author
- Eriksson Linsmeier, Cecilia LU ; Prinz, Christelle LU ; Pettersson, Lina LU ; Caroff, Philippe LU ; Samuelson, Lars LU ; Schouenborg, Jens LU ; Montelius, Lars LU and Danielsen, Nils LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nano Letters
- volume
- 9
- issue
- 12
- pages
- 4184 - 4190
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000272395400039
- pmid:19845389
- scopus:71949096139
- pmid:19845389
- ISSN
- 1530-6992
- DOI
- 10.1021/nl902413x
- language
- English
- LU publication?
- yes
- id
- 193b7c91-23e3-4253-8c90-04c3dfdc49e8 (old id 1500121)
- date added to LUP
- 2016-04-01 14:13:12
- date last changed
- 2024-06-20 00:47:54
@article{193b7c91-23e3-4253-8c90-04c3dfdc49e8, abstract = {{We investigated the brain-tissue response to nanowire implantations in the rat striatum after 1, 6, and 12 weeks using immunohistochemistry. The nanowires could be visualized in the scar by confocal microscopy (through the scattered laser light). For the nanowire-implanted animals, there is a significant astrocyte response at week 1 compared to controls. The nanowires are phagocytized by ED1 positive microglia, and some of them are degraded and/or transported away from the brain.}}, author = {{Eriksson Linsmeier, Cecilia and Prinz, Christelle and Pettersson, Lina and Caroff, Philippe and Samuelson, Lars and Schouenborg, Jens and Montelius, Lars and Danielsen, Nils}}, issn = {{1530-6992}}, language = {{eng}}, number = {{12}}, pages = {{4184--4190}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Nano Letters}}, title = {{Nanowire Biocompatibility in the Brain - Looking for a Needle in a 3D Stack.}}, url = {{http://dx.doi.org/10.1021/nl902413x}}, doi = {{10.1021/nl902413x}}, volume = {{9}}, year = {{2009}}, }