Intracranial manifestations in SAPHO syndrome: the first case report in literature.
(2012) In Rheumatology International 32(6). p.1797-1799- Abstract
- A 41-year-old woman with SAPHO syndrome presented with numbness of her left arm followed by a generalized seizure. Computed tomography and magnetic resonance imaging of the brain revealed a small ring enhancing lesion in the right parietal lobe with adjacent meningeal thickening and enhancement. Surgical removal and histopathology showed evidence of severe chronic sterile inflammation and no malignant cell. Symptoms recurred and a lesion were again detected on radiological follow-up, but improvement occurred following treatment with antibiotics and biphosphonate, achieving a low inflammatory activity, reduction in CNS lesions and relative clinical well-being. This is a first report in literature about the central nervous system involvement... (More)
- A 41-year-old woman with SAPHO syndrome presented with numbness of her left arm followed by a generalized seizure. Computed tomography and magnetic resonance imaging of the brain revealed a small ring enhancing lesion in the right parietal lobe with adjacent meningeal thickening and enhancement. Surgical removal and histopathology showed evidence of severe chronic sterile inflammation and no malignant cell. Symptoms recurred and a lesion were again detected on radiological follow-up, but improvement occurred following treatment with antibiotics and biphosphonate, achieving a low inflammatory activity, reduction in CNS lesions and relative clinical well-being. This is a first report in literature about the central nervous system involvement in a patient with SAPHO syndrome. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1581424
- author
- Abul-Kasim, Kasim LU ; Nilsson, Tomas and Turesson, Carl LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Rheumatology International
- volume
- 32
- issue
- 6
- pages
- 1797 - 1799
- publisher
- Springer
- external identifiers
-
- wos:000305680300050
- pmid:20352220
- scopus:84863877507
- pmid:20352220
- ISSN
- 1437-160X
- DOI
- 10.1007/s00296-010-1464-8
- language
- English
- LU publication?
- yes
- id
- d7e7eea2-4bc8-4550-a69e-2fd62684f2f4 (old id 1581424)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/20352220?dopt=Abstract
- date added to LUP
- 2016-04-01 14:43:30
- date last changed
- 2022-04-30 03:24:52
@article{d7e7eea2-4bc8-4550-a69e-2fd62684f2f4,
abstract = {{A 41-year-old woman with SAPHO syndrome presented with numbness of her left arm followed by a generalized seizure. Computed tomography and magnetic resonance imaging of the brain revealed a small ring enhancing lesion in the right parietal lobe with adjacent meningeal thickening and enhancement. Surgical removal and histopathology showed evidence of severe chronic sterile inflammation and no malignant cell. Symptoms recurred and a lesion were again detected on radiological follow-up, but improvement occurred following treatment with antibiotics and biphosphonate, achieving a low inflammatory activity, reduction in CNS lesions and relative clinical well-being. This is a first report in literature about the central nervous system involvement in a patient with SAPHO syndrome.}},
author = {{Abul-Kasim, Kasim and Nilsson, Tomas and Turesson, Carl}},
issn = {{1437-160X}},
language = {{eng}},
number = {{6}},
pages = {{1797--1799}},
publisher = {{Springer}},
series = {{Rheumatology International}},
title = {{Intracranial manifestations in SAPHO syndrome: the first case report in literature.}},
url = {{http://dx.doi.org/10.1007/s00296-010-1464-8}},
doi = {{10.1007/s00296-010-1464-8}},
volume = {{32}},
year = {{2012}},
}