In Vitro Activity of Lipopeptides Pal-Lys-Lys-NH2 and Pal-Lys-Lys Alone and in Combination with Antimicrobial Agents against Multiresistant Gram-positive Cocci.
(2007) In Antimicrobial Agents and Chemotherapy 51(1). p.354-358- Abstract
- The in vitro activities of the lipopeptides pahnitoyl (Pal)-Lys-Lys-NH2 and Pal-Lys-Lys against gram-positive cocci were investigated. Enterococci and streptococci demonstrated higher susceptibilities than staphylococci and Rhodococcus equi. A positive interaction was shown when the lipopeptides were combined with beta-lactams and vancomycin. These results suggest that lipopeptides are promising candidates for antimicrobial therapy for infections caused by gram-positive organisms.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/162162
- author
- Kamysz, Wojciech ; Silvestri, Carmela ; Cirioni, Oscar ; Giacometti, Andrea ; Licci, Alberto ; Vittoria, Agnese Della ; Okroj, Marcin LU and Scalise, Giorgio
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Antimicrobial Agents and Chemotherapy
- volume
- 51
- issue
- 1
- pages
- 354 - 358
- publisher
- American Society for Microbiology
- external identifiers
-
- wos:000243214200048
- scopus:33845984047
- ISSN
- 1098-6596
- DOI
- 10.1128/AAC.00344-06
- language
- English
- LU publication?
- yes
- id
- b3b4e5a2-fad5-439c-8a51-051656b92dfc (old id 162162)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17060532&dopt=Abstract
- date added to LUP
- 2016-04-01 15:24:06
- date last changed
- 2022-01-28 05:10:39
@article{b3b4e5a2-fad5-439c-8a51-051656b92dfc, abstract = {{The in vitro activities of the lipopeptides pahnitoyl (Pal)-Lys-Lys-NH2 and Pal-Lys-Lys against gram-positive cocci were investigated. Enterococci and streptococci demonstrated higher susceptibilities than staphylococci and Rhodococcus equi. A positive interaction was shown when the lipopeptides were combined with beta-lactams and vancomycin. These results suggest that lipopeptides are promising candidates for antimicrobial therapy for infections caused by gram-positive organisms.}}, author = {{Kamysz, Wojciech and Silvestri, Carmela and Cirioni, Oscar and Giacometti, Andrea and Licci, Alberto and Vittoria, Agnese Della and Okroj, Marcin and Scalise, Giorgio}}, issn = {{1098-6596}}, language = {{eng}}, number = {{1}}, pages = {{354--358}}, publisher = {{American Society for Microbiology}}, series = {{Antimicrobial Agents and Chemotherapy}}, title = {{In Vitro Activity of Lipopeptides Pal-Lys-Lys-NH2 and Pal-Lys-Lys Alone and in Combination with Antimicrobial Agents against Multiresistant Gram-positive Cocci.}}, url = {{http://dx.doi.org/10.1128/AAC.00344-06}}, doi = {{10.1128/AAC.00344-06}}, volume = {{51}}, year = {{2007}}, }