Changes in high-frequency QRS components are more sensitive than ST segment deviation for detecting acute coronary artery occlusion
(2000) In Journal of the American College of Cardiology 36(6). p.1827-1834- Abstract
- OBJECTIVES
This study describes changes in high-frequency QRS components (HF-QRS) during percutaneous transluminal coronary angioplasty (PTCA) and compares the ability of these changes in HF-QRS and ST-segment deviation in the standard 12-lead electrocardiogram (ECG) to detect acute coronary artery occlusion.
BACKGROUND
Previous studies have shown decreased HF-QRS in the frequency range of 150–250 Hz during acute myocardial ischemia. It would be important to know whether the high-frequency analysis could add information to that available from the ST segments in the standard ECG.
METHODS
The study population consisted of 52 patients undergoing... (More) - OBJECTIVES
This study describes changes in high-frequency QRS components (HF-QRS) during percutaneous transluminal coronary angioplasty (PTCA) and compares the ability of these changes in HF-QRS and ST-segment deviation in the standard 12-lead electrocardiogram (ECG) to detect acute coronary artery occlusion.
BACKGROUND
Previous studies have shown decreased HF-QRS in the frequency range of 150–250 Hz during acute myocardial ischemia. It would be important to know whether the high-frequency analysis could add information to that available from the ST segments in the standard ECG.
METHODS
The study population consisted of 52 patients undergoing prolonged balloon occlusion during PTCA. Signal-averaged electrocardiograms (SAECG) were recorded prior to and during the balloon inflation. The HF-QRS were determined within a bandwidth of 150–250 Hz in the preinflation and inflation SAECGs. The ST-segment deviation during inflation was determined in the standard frequency range.
RESULTS
The sensitivity for detecting acute coronary artery occlusion was 88% using the high-frequency method. In 71% of the patients there was ST elevation during inflation. If both ST elevation and depression were considered, the sensitivity was 79%. The sensitivity was significantly higher using the high-frequency method, p < 0.002, compared with the assessment of ST elevation.
CONCLUSIONS
Acute coronary artery occlusion is detected with higher sensitivity using high-frequency QRS analysis compared with conventional assessment of ST segments. This result suggests that analysis of HF-QRS could provide an adjunctive tool with high sensitivity for detecting acute myocardial ischemia. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1758850
- author
- Pettersson, Jonas LU ; Carro, E. ; Edenbrandt, Lars LU ; Ringborn, Michael LU ; Sörnmo, Leif LU ; Warren, Stafford G. and Wagner, Galen S.
- organization
- publishing date
- 2000
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of the American College of Cardiology
- volume
- 36
- issue
- 6
- pages
- 1827 - 1834
- publisher
- Elsevier
- external identifiers
-
- scopus:0034669446
- ISSN
- 0735-1097
- DOI
- 10.1016/S0735-1097(00)00936-0
- language
- English
- LU publication?
- yes
- id
- 8d40cf1d-de79-44d9-a347-d1dbd2e9a714 (old id 1758850)
- date added to LUP
- 2016-04-04 07:46:49
- date last changed
- 2022-05-01 05:36:26
@article{8d40cf1d-de79-44d9-a347-d1dbd2e9a714,
abstract = {{OBJECTIVES<br/><br>
<br/><br>
This study describes changes in high-frequency QRS components (HF-QRS) during percutaneous transluminal coronary angioplasty (PTCA) and compares the ability of these changes in HF-QRS and ST-segment deviation in the standard 12-lead electrocardiogram (ECG) to detect acute coronary artery occlusion.<br/><br>
<br/><br>
BACKGROUND<br/><br>
<br/><br>
Previous studies have shown decreased HF-QRS in the frequency range of 150–250 Hz during acute myocardial ischemia. It would be important to know whether the high-frequency analysis could add information to that available from the ST segments in the standard ECG.<br/><br>
<br/><br>
METHODS<br/><br>
<br/><br>
The study population consisted of 52 patients undergoing prolonged balloon occlusion during PTCA. Signal-averaged electrocardiograms (SAECG) were recorded prior to and during the balloon inflation. The HF-QRS were determined within a bandwidth of 150–250 Hz in the preinflation and inflation SAECGs. The ST-segment deviation during inflation was determined in the standard frequency range.<br/><br>
<br/><br>
RESULTS<br/><br>
<br/><br>
The sensitivity for detecting acute coronary artery occlusion was 88% using the high-frequency method. In 71% of the patients there was ST elevation during inflation. If both ST elevation and depression were considered, the sensitivity was 79%. The sensitivity was significantly higher using the high-frequency method, p < 0.002, compared with the assessment of ST elevation.<br/><br>
<br/><br>
CONCLUSIONS<br/><br>
<br/><br>
Acute coronary artery occlusion is detected with higher sensitivity using high-frequency QRS analysis compared with conventional assessment of ST segments. This result suggests that analysis of HF-QRS could provide an adjunctive tool with high sensitivity for detecting acute myocardial ischemia.}},
author = {{Pettersson, Jonas and Carro, E. and Edenbrandt, Lars and Ringborn, Michael and Sörnmo, Leif and Warren, Stafford G. and Wagner, Galen S.}},
issn = {{0735-1097}},
language = {{eng}},
number = {{6}},
pages = {{1827--1834}},
publisher = {{Elsevier}},
series = {{Journal of the American College of Cardiology}},
title = {{Changes in high-frequency QRS components are more sensitive than ST segment deviation for detecting acute coronary artery occlusion}},
url = {{http://dx.doi.org/10.1016/S0735-1097(00)00936-0}},
doi = {{10.1016/S0735-1097(00)00936-0}},
volume = {{36}},
year = {{2000}},
}