Antiproliferative activity of extracts of some Bolivian medicinal plants
(2010) In Journal of Medicinal Plants Research 4(21). p.2204-2210- Abstract
- Twenty-six plant species from the native flora used in Bolivian folk medicine were selected for studies of bioactivity. They belonged to the following families namely: Asteraceae (11), Brassicaceae (1), Cactaceae (1), Caesalpinaceae (2), Chenopodiaceae (1), Frankeniaceae (1), Geraniaceae (1), Laureaceae (1), Oxalidaceae (1), Piperaceae (1), Plantaginaceae (1), Rosaceae (1), Solanaceae (1) and Verbenaceae (2). Their effects on the proliferation of colon cancer cells (Caco-2) were studied using the WST-1 reagent. The results indicated that four out of 26 ethanolic extracts had a significant antiproliferative activity in this assay from (Schkuhria pinnata, Piper longestylosum, Parastrephia lepidophylla and Erodium cicutarium). The bioactivity... (More)
- Twenty-six plant species from the native flora used in Bolivian folk medicine were selected for studies of bioactivity. They belonged to the following families namely: Asteraceae (11), Brassicaceae (1), Cactaceae (1), Caesalpinaceae (2), Chenopodiaceae (1), Frankeniaceae (1), Geraniaceae (1), Laureaceae (1), Oxalidaceae (1), Piperaceae (1), Plantaginaceae (1), Rosaceae (1), Solanaceae (1) and Verbenaceae (2). Their effects on the proliferation of colon cancer cells (Caco-2) were studied using the WST-1 reagent. The results indicated that four out of 26 ethanolic extracts had a significant antiproliferative activity in this assay from (Schkuhria pinnata, Piper longestylosum, Parastrephia lepidophylla and Erodium cicutarium). The bioactivity of the extracts was correlated with the phytochemical characterization. Further studies of the mechanism of action of the bioactive extracts are needed. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1811446
- author
- Rodrigo, Gloria LU ; Almanza, Giovanna R. ; Åkesson, Björn LU and Duan, Rui-Dong LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- colon cancer, cell proliferation, Bolivian plants
- in
- Journal of Medicinal Plants Research
- volume
- 4
- issue
- 21
- pages
- 2204 - 2210
- publisher
- Academic Journals
- external identifiers
-
- wos:000285689600006
- scopus:78650584427
- ISSN
- 1996-0875
- language
- English
- LU publication?
- yes
- id
- 8794b6bb-567c-4da0-aea3-d40e8b09c57b (old id 1811446)
- alternative location
- http://www.academicjournals.org/JMPR/abstracts/abstracts/abstracts2010/4Nov/Rodrigo%20et%20al.htm
- date added to LUP
- 2016-04-01 13:36:42
- date last changed
- 2024-01-09 15:58:00
@article{8794b6bb-567c-4da0-aea3-d40e8b09c57b, abstract = {{Twenty-six plant species from the native flora used in Bolivian folk medicine were selected for studies of bioactivity. They belonged to the following families namely: Asteraceae (11), Brassicaceae (1), Cactaceae (1), Caesalpinaceae (2), Chenopodiaceae (1), Frankeniaceae (1), Geraniaceae (1), Laureaceae (1), Oxalidaceae (1), Piperaceae (1), Plantaginaceae (1), Rosaceae (1), Solanaceae (1) and Verbenaceae (2). Their effects on the proliferation of colon cancer cells (Caco-2) were studied using the WST-1 reagent. The results indicated that four out of 26 ethanolic extracts had a significant antiproliferative activity in this assay from (Schkuhria pinnata, Piper longestylosum, Parastrephia lepidophylla and Erodium cicutarium). The bioactivity of the extracts was correlated with the phytochemical characterization. Further studies of the mechanism of action of the bioactive extracts are needed.}}, author = {{Rodrigo, Gloria and Almanza, Giovanna R. and Åkesson, Björn and Duan, Rui-Dong}}, issn = {{1996-0875}}, keywords = {{colon cancer; cell proliferation; Bolivian plants}}, language = {{eng}}, number = {{21}}, pages = {{2204--2210}}, publisher = {{Academic Journals}}, series = {{Journal of Medicinal Plants Research}}, title = {{Antiproliferative activity of extracts of some Bolivian medicinal plants}}, url = {{http://www.academicjournals.org/JMPR/abstracts/abstracts/abstracts2010/4Nov/Rodrigo%20et%20al.htm}}, volume = {{4}}, year = {{2010}}, }