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Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining "Shrunken Pore Syndrome"

Grubb, A. LU orcid (2017) p.225-240
Abstract

Cystatin C, a basic nonglycosylated 13.3 kDa protein comprising a single polypeptide chain of 120 amino acid residues, is produced at a stable rate from a housekeeping gene in all nucleated cells and eliminated from the circulation by free filtration through the glomerular membranes as described in the first edition of "Biomarkers of Kidney Disease." This discourse will report some of the progress in the use of cystatin C as a multifaceted marker of kidney disease, which has occurred since then, including its role in identifying the novel syndrome called "Shrunken Pore Syndrome."

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Biomarker, Creatinine, Cystatin C, GFR-estimating equations, Internal and external validation, Renal reserve, Shrunken Pore Syndrome
host publication
Biomarkers of Kidney Disease
editor
Edelstein, C.L.
edition
2
pages
16 pages
publisher
Elsevier
external identifiers
  • scopus:85010190522
ISBN
9780128030141
DOI
10.1016/B978-0-12-803014-1.00005-4
language
English
LU publication?
yes
id
1c32d304-1a34-4770-836b-ebf87ecea8aa
date added to LUP
2017-02-06 11:16:31
date last changed
2023-03-22 02:06:50
@inbook{1c32d304-1a34-4770-836b-ebf87ecea8aa,
  abstract     = {{<p>Cystatin C, a basic nonglycosylated 13.3 kDa protein comprising a single polypeptide chain of 120 amino acid residues, is produced at a stable rate from a housekeeping gene in all nucleated cells and eliminated from the circulation by free filtration through the glomerular membranes as described in the first edition of "Biomarkers of Kidney Disease." This discourse will report some of the progress in the use of cystatin C as a multifaceted marker of kidney disease, which has occurred since then, including its role in identifying the novel syndrome called "Shrunken Pore Syndrome."</p>}},
  author       = {{Grubb, A.}},
  booktitle    = {{Biomarkers of Kidney Disease}},
  editor       = {{Edelstein, C.L.}},
  isbn         = {{9780128030141}},
  keywords     = {{Biomarker; Creatinine; Cystatin C; GFR-estimating equations; Internal and external validation; Renal reserve; Shrunken Pore Syndrome}},
  language     = {{eng}},
  pages        = {{225--240}},
  publisher    = {{Elsevier}},
  title        = {{Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining "Shrunken Pore Syndrome"}},
  url          = {{http://dx.doi.org/10.1016/B978-0-12-803014-1.00005-4}},
  doi          = {{10.1016/B978-0-12-803014-1.00005-4}},
  year         = {{2017}},
}