The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography
(2016) 13th International Workshop on Breast Imaging, IWDM 2016 In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 9699. p.282-288- Abstract
Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P =... (More)
Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P = 0.01). There was no evidence for a difference in mean pressure or standard deviation of the MI image between symptomatic and contralateral asymptomatic breasts (P = 0.24 and 0.68). The results support that it is possible to use MI to distinguish malignant cancers from normal breast tissue. Still, further investigations of the characteristics of benign lesions are necessary to ascertain the usefulness of the system.
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- author
- Dustler, Magnus LU ; Förnvik, Daniel LU ; Timberg, Pontus LU ; Petersson, Hannie LU ; Tingberg, Anders LU and Zackrisson, Sophia LU
- organization
- publishing date
- 2016
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Elastography, Mammography, Mechanical imaging, Screening
- host publication
- Breast Imaging : 13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings - 13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings
- series title
- Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
- editor
- Tingberg, Anders ; Lång, Kristina and Timberg, Pontus
- volume
- 9699
- pages
- 7 pages
- publisher
- Springer
- conference name
- 13th International Workshop on Breast Imaging, IWDM 2016
- conference location
- Malmo, Sweden
- conference dates
- 2016-06-19 - 2016-06-22
- external identifiers
-
- scopus:84977553497
- wos:000386324200036
- ISSN
- 16113349
- 03029743
- ISBN
- 9783319415451
- 978-3-319-41546-8
- DOI
- 10.1007/978-3-319-41546-8_36
- language
- English
- LU publication?
- yes
- id
- 2267bf40-208f-4d18-8782-dc370f5febc3
- date added to LUP
- 2016-07-25 12:47:06
- date last changed
- 2024-07-12 14:00:40
@inproceedings{2267bf40-208f-4d18-8782-dc370f5febc3, abstract = {{<p>Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P = 0.01). There was no evidence for a difference in mean pressure or standard deviation of the MI image between symptomatic and contralateral asymptomatic breasts (P = 0.24 and 0.68). The results support that it is possible to use MI to distinguish malignant cancers from normal breast tissue. Still, further investigations of the characteristics of benign lesions are necessary to ascertain the usefulness of the system.</p>}}, author = {{Dustler, Magnus and Förnvik, Daniel and Timberg, Pontus and Petersson, Hannie and Tingberg, Anders and Zackrisson, Sophia}}, booktitle = {{Breast Imaging : 13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings}}, editor = {{Tingberg, Anders and Lång, Kristina and Timberg, Pontus}}, isbn = {{9783319415451}}, issn = {{16113349}}, keywords = {{Elastography; Mammography; Mechanical imaging; Screening}}, language = {{eng}}, pages = {{282--288}}, publisher = {{Springer}}, series = {{Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)}}, title = {{The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography}}, url = {{http://dx.doi.org/10.1007/978-3-319-41546-8_36}}, doi = {{10.1007/978-3-319-41546-8_36}}, volume = {{9699}}, year = {{2016}}, }