Proteomics-protein profiling technology: the trend towards a microfabricated toolbox concept
(2001) In Trac. Trends in Analytical Chemistry 20(5). p.225-231- Abstract
- The use of mono-crystalline silicon microstructures for high-speed and high sensitivity protein mapping and protein identification is presented as an important contribution within the field of proteomics. The various approaches for handling minute amounts of protein sample are described. Piezoelectric dispensing units developed in-house are being used for sample-handling and the generation of 60-pl droplets, interfacing with high-density microchip MALDI-TOF MS target plates having an array density of 4000 nanovials/square inch. Examples of applications to microtechnology, and future trends in our research are outlined. (C) 2001 Elsevier Science B.V. All rights reserved.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2376380
- author
- Laurell, Thomas LU ; Nilsson, J. and Marko-Varga, György LU
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- proteomics, microtechnology, mass spectrometry, piezoelectric, dispensing, nanovial, FLIGHT MASS-SPECTROMETRY, SAMPLE PREPARATION, LASER, MICRODISSECTION, CHROMATOGRAPHY, SEPARATIONS, SYSTEMS
- in
- Trac. Trends in Analytical Chemistry
- volume
- 20
- issue
- 5
- pages
- 225 - 231
- publisher
- Elsevier
- external identifiers
-
- wos:000169278500006
- scopus:0035338540
- ISSN
- 0165-9936
- DOI
- 10.1016/s0165-9936(01)00061-9
- language
- English
- LU publication?
- yes
- id
- 200e8f4b-6587-4232-b6fe-f78e45e0d960 (old id 2376380)
- date added to LUP
- 2016-04-01 16:51:27
- date last changed
- 2022-01-28 22:39:27
@article{200e8f4b-6587-4232-b6fe-f78e45e0d960, abstract = {{The use of mono-crystalline silicon microstructures for high-speed and high sensitivity protein mapping and protein identification is presented as an important contribution within the field of proteomics. The various approaches for handling minute amounts of protein sample are described. Piezoelectric dispensing units developed in-house are being used for sample-handling and the generation of 60-pl droplets, interfacing with high-density microchip MALDI-TOF MS target plates having an array density of 4000 nanovials/square inch. Examples of applications to microtechnology, and future trends in our research are outlined. (C) 2001 Elsevier Science B.V. All rights reserved.}}, author = {{Laurell, Thomas and Nilsson, J. and Marko-Varga, György}}, issn = {{0165-9936}}, keywords = {{proteomics; microtechnology; mass spectrometry; piezoelectric; dispensing; nanovial; FLIGHT MASS-SPECTROMETRY; SAMPLE PREPARATION; LASER; MICRODISSECTION; CHROMATOGRAPHY; SEPARATIONS; SYSTEMS}}, language = {{eng}}, number = {{5}}, pages = {{225--231}}, publisher = {{Elsevier}}, series = {{Trac. Trends in Analytical Chemistry}}, title = {{Proteomics-protein profiling technology: the trend towards a microfabricated toolbox concept}}, url = {{http://dx.doi.org/10.1016/s0165-9936(01)00061-9}}, doi = {{10.1016/s0165-9936(01)00061-9}}, volume = {{20}}, year = {{2001}}, }