Collagen VI Encodes Antimicrobial Activity: Novel Innate Host Defense Properties of the Extracellular Matrix.
(2012) In Journal of Innate Immunity 4(4). p.371-376- Abstract
- Collagen type VI is a subepithelial extracellular matrix component in airways and an adhesive substrate for oral pathogens [Bober et al.: J Innate Immun 2010;2:160-166]. Here, we report that collagen VI displays a dose-dependent antimicrobial activity against group A, C, and G streptococci by membrane disruption in physiological conditions. The data disclose previously unrecognized aspects of the extracellular matrix in innate host defense.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2432163
- author
- M Abdillahi, Suado LU ; Balvanović, Selma ; Baumgarten, Maria LU and Mörgelin, Matthias LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Innate Immunity
- volume
- 4
- issue
- 4
- pages
- 371 - 376
- publisher
- Karger
- external identifiers
-
- wos:000305819800006
- pmid:22398575
- scopus:84863335308
- ISSN
- 1662-811X
- DOI
- 10.1159/000335239
- language
- English
- LU publication?
- yes
- id
- 74c5e330-ab74-414e-9c9f-72ad97b15723 (old id 2432163)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22398575?dopt=Abstract
- date added to LUP
- 2016-04-04 08:55:15
- date last changed
- 2022-01-29 07:44:57
@article{74c5e330-ab74-414e-9c9f-72ad97b15723, abstract = {{Collagen type VI is a subepithelial extracellular matrix component in airways and an adhesive substrate for oral pathogens [Bober et al.: J Innate Immun 2010;2:160-166]. Here, we report that collagen VI displays a dose-dependent antimicrobial activity against group A, C, and G streptococci by membrane disruption in physiological conditions. The data disclose previously unrecognized aspects of the extracellular matrix in innate host defense.}}, author = {{M Abdillahi, Suado and Balvanović, Selma and Baumgarten, Maria and Mörgelin, Matthias}}, issn = {{1662-811X}}, language = {{eng}}, number = {{4}}, pages = {{371--376}}, publisher = {{Karger}}, series = {{Journal of Innate Immunity}}, title = {{Collagen VI Encodes Antimicrobial Activity: Novel Innate Host Defense Properties of the Extracellular Matrix.}}, url = {{http://dx.doi.org/10.1159/000335239}}, doi = {{10.1159/000335239}}, volume = {{4}}, year = {{2012}}, }