Occupational Risk Factors for Systemic Lupus Erythematosus: a Nationwide Study Based on Hospitalizations in Sweden.
(2012) In Journal of Rheumatology 39(4). p.743-751- Abstract
- OBJECTIVE: To investigate possible associations between occupation and hospitalization for systemic lupus erythematosus (SLE) in a nationwide study.
METHODS: A nationwide database was constructed in Sweden by linking the Swedish Census to the Hospital Discharge Register to obtain data on all first hospitalizations with a primary or secondary diagnosis of SLE in adults during the study period (1970 to 2008). Standardized incidence ratios (SIR) and 95% CI were calculated for different occupations. Two cohorts were defined based on occupational titles recorded in Swedish census data in 1970 and 1980.
RESULTS: A total of 8921 male and 42290 female hospitalizations for SLE were retrieved in individuals... (More) - OBJECTIVE: To investigate possible associations between occupation and hospitalization for systemic lupus erythematosus (SLE) in a nationwide study.
METHODS: A nationwide database was constructed in Sweden by linking the Swedish Census to the Hospital Discharge Register to obtain data on all first hospitalizations with a primary or secondary diagnosis of SLE in adults during the study period (1970 to 2008). Standardized incidence ratios (SIR) and 95% CI were calculated for different occupations. Two cohorts were defined based on occupational titles recorded in Swedish census data in 1970 and 1980.
RESULTS: A total of 8921 male and 42290 female hospitalizations for SLE were retrieved in individuals aged over 15 years. High education (> 12 yrs) was associated with a lower risk of hospitalization for SLE among both women (SIR = 0.73) and men (SIR = 0.72). Among men with the same occupation in 2 consecutive censuses, increased risks (SIR) > 2.0 were present among artistic workers (2.52); shop managers and assistants (3.63); miners and quarry workers (6.04); shoe and leather workers (6.93); plumbers (2.21); other construction workers (2.08); glass, ceramic and tile workers (4.43); chimney sweeps (4.54); and military personnel (3.01). Among women with the same occupation in 2 consecutive censuses, no occupation was associated with SIR > 2.0.
CONCLUSION: Occupation may carry significantly increased risk of hospital admission for SLE. Especially among men, several occupations were associated with increased risks for SLE. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2432335
- author
- Li, Xinjun LU ; Sundquist, Jan LU ; Sundquist, Kristina LU and Zöller, Bengt LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Rheumatology
- volume
- 39
- issue
- 4
- pages
- 743 - 751
- publisher
- Journal of Rheumatology Publishing Company Limited
- external identifiers
-
- wos:000302840800015
- pmid:22382347
- scopus:84859475501
- pmid:22382347
- ISSN
- 0315-162X
- DOI
- 10.3899/jrheum.110789
- language
- English
- LU publication?
- yes
- id
- d43e2be0-d4a6-472a-a19a-b8ceb7b1ce51 (old id 2432335)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22382347?dopt=Abstract
- date added to LUP
- 2016-04-04 08:04:04
- date last changed
- 2022-03-07 21:07:50
@article{d43e2be0-d4a6-472a-a19a-b8ceb7b1ce51, abstract = {{OBJECTIVE: To investigate possible associations between occupation and hospitalization for systemic lupus erythematosus (SLE) in a nationwide study. <br/><br> <br/><br> METHODS: A nationwide database was constructed in Sweden by linking the Swedish Census to the Hospital Discharge Register to obtain data on all first hospitalizations with a primary or secondary diagnosis of SLE in adults during the study period (1970 to 2008). Standardized incidence ratios (SIR) and 95% CI were calculated for different occupations. Two cohorts were defined based on occupational titles recorded in Swedish census data in 1970 and 1980. <br/><br> <br/><br> RESULTS: A total of 8921 male and 42290 female hospitalizations for SLE were retrieved in individuals aged over 15 years. High education (> 12 yrs) was associated with a lower risk of hospitalization for SLE among both women (SIR = 0.73) and men (SIR = 0.72). Among men with the same occupation in 2 consecutive censuses, increased risks (SIR) > 2.0 were present among artistic workers (2.52); shop managers and assistants (3.63); miners and quarry workers (6.04); shoe and leather workers (6.93); plumbers (2.21); other construction workers (2.08); glass, ceramic and tile workers (4.43); chimney sweeps (4.54); and military personnel (3.01). Among women with the same occupation in 2 consecutive censuses, no occupation was associated with SIR > 2.0. <br/><br> <br/><br> CONCLUSION: Occupation may carry significantly increased risk of hospital admission for SLE. Especially among men, several occupations were associated with increased risks for SLE.}}, author = {{Li, Xinjun and Sundquist, Jan and Sundquist, Kristina and Zöller, Bengt}}, issn = {{0315-162X}}, language = {{eng}}, number = {{4}}, pages = {{743--751}}, publisher = {{Journal of Rheumatology Publishing Company Limited}}, series = {{Journal of Rheumatology}}, title = {{Occupational Risk Factors for Systemic Lupus Erythematosus: a Nationwide Study Based on Hospitalizations in Sweden.}}, url = {{http://dx.doi.org/10.3899/jrheum.110789}}, doi = {{10.3899/jrheum.110789}}, volume = {{39}}, year = {{2012}}, }