Radiation dose reduction in CT of the brain: can advanced noise filtering compensate for loss of image quality?
Siemund, Roger LU ; Löve, Askell LU ; van Westen, Danielle LU
; Stenberg, Lars
LU
; Petersen, C
and Björkman-Burtscher, Isabella
LU
(2012)
In Acta radiologica (Stockholm, Sweden : 1987)
53(4).
p.468-472
- Abstract
- Background: Computed tomography (CT) of the brain is performed with high local doses due to high demands on low contrast resolution. Advanced algorithms for noise reduction might be able to preserve critical image information when reducing radiation dose.PurposeTo evaluate the effect of advanced noise filtering on image quality in brain CT acquired with reduced radiation dose.
Material and Methods: Thirty patients referred for non-enhanced CT of the brain were examined with two helical protocols: normal dose (ND, CTDI(vol) 57 mGy) and low dose (LD, CTDI(vol) 40 mGy) implying a 30% radiation dose reduction. Images from the LD examinations were also postprocessed with a noise reduction software with non-linear filters... (More) - Background: Computed tomography (CT) of the brain is performed with high local doses due to high demands on low contrast resolution. Advanced algorithms for noise reduction might be able to preserve critical image information when reducing radiation dose.PurposeTo evaluate the effect of advanced noise filtering on image quality in brain CT acquired with reduced radiation dose.
Material and Methods: Thirty patients referred for non-enhanced CT of the brain were examined with two helical protocols: normal dose (ND, CTDI(vol) 57 mGy) and low dose (LD, CTDI(vol) 40 mGy) implying a 30% radiation dose reduction. Images from the LD examinations were also postprocessed with a noise reduction software with non-linear filters (SharpView CT), creating filtered low dose images (FLD) for each patient. The three image stacks for each patient were presented side by side in randomized order. Five radiologists, blinded for dose level and filtering, ranked these three axial image stacks (ND, LD, FLD) as best to poorest (1 to 3) regarding three image quality criteria. Measurements of mean Hounsfield units (HU) and standard deviation (SD) of the HU were calculated for large region of interest in the centrum semiovale as a measure for noise.
Results: Ranking results in pooled data showed that the advanced noise filtering significantly improved the image quality in FLD as compared to LD images for all tested criteria. No significant differences in image quality were found between ND examinations and FLD. However, there was a notable inter-reader spread of the ranking. SD values were 15% higher for LD as compared to ND and FLD.ConclusionThe advanced noise filtering clearly improves image quality of CT examinations of the brain. This effect can be used to significantly lower radiation dose. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2519366
- author
- Siemund, Roger
LU
; Löve, Askell
LU
; van Westen, Danielle
LU
; Stenberg, Lars
LU
; Petersen, C
and Björkman-Burtscher, Isabella
LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta radiologica (Stockholm, Sweden : 1987)
- volume
- 53
- issue
- 4
- pages
- 468 - 472
- publisher
- SAGE Publications
- external identifiers
-
- wos:000304388200017
- pmid:22509068
- scopus:84860616718
- pmid:22509068
- ISSN
- 1600-0455
- DOI
- 10.1258/ar.2012.110629
- language
- English
- LU publication?
- yes
- id
- e5c4e59f-6bb5-4039-acb0-852ea6cf3950 (old id 2519366)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22509068?dopt=Abstract
- date added to LUP
- 2016-04-04 09:28:57
- date last changed
- 2022-01-29 18:05:32
@article{e5c4e59f-6bb5-4039-acb0-852ea6cf3950,
abstract = {{Background: Computed tomography (CT) of the brain is performed with high local doses due to high demands on low contrast resolution. Advanced algorithms for noise reduction might be able to preserve critical image information when reducing radiation dose.PurposeTo evaluate the effect of advanced noise filtering on image quality in brain CT acquired with reduced radiation dose.<br/><br>
<br/><br>
Material and Methods: Thirty patients referred for non-enhanced CT of the brain were examined with two helical protocols: normal dose (ND, CTDI(vol) 57 mGy) and low dose (LD, CTDI(vol) 40 mGy) implying a 30% radiation dose reduction. Images from the LD examinations were also postprocessed with a noise reduction software with non-linear filters (SharpView CT), creating filtered low dose images (FLD) for each patient. The three image stacks for each patient were presented side by side in randomized order. Five radiologists, blinded for dose level and filtering, ranked these three axial image stacks (ND, LD, FLD) as best to poorest (1 to 3) regarding three image quality criteria. Measurements of mean Hounsfield units (HU) and standard deviation (SD) of the HU were calculated for large region of interest in the centrum semiovale as a measure for noise.<br/><br>
<br/><br>
Results: Ranking results in pooled data showed that the advanced noise filtering significantly improved the image quality in FLD as compared to LD images for all tested criteria. No significant differences in image quality were found between ND examinations and FLD. However, there was a notable inter-reader spread of the ranking. SD values were 15% higher for LD as compared to ND and FLD.ConclusionThe advanced noise filtering clearly improves image quality of CT examinations of the brain. This effect can be used to significantly lower radiation dose.}},
author = {{Siemund, Roger and Löve, Askell and van Westen, Danielle and Stenberg, Lars and Petersen, C and Björkman-Burtscher, Isabella}},
issn = {{1600-0455}},
language = {{eng}},
number = {{4}},
pages = {{468--472}},
publisher = {{SAGE Publications}},
series = {{Acta radiologica (Stockholm, Sweden : 1987)}},
title = {{Radiation dose reduction in CT of the brain: can advanced noise filtering compensate for loss of image quality?}},
url = {{http://dx.doi.org/10.1258/ar.2012.110629}},
doi = {{10.1258/ar.2012.110629}},
volume = {{53}},
year = {{2012}},
}