A Crystallographic Study of Platinum(II) Complexes
(1996)- Abstract
- Single crystal structural data have been used to estimate the influence of the X, Y and Z ligands on the Pt‹L bond length in [PtLXYZ] complexes, i.e. the ground state cis- and trans-influence. Cl or S were selected as indicator ligands, L, for these studies. Ligands with soft donor atoms, such as sulfur, carbon and silicon have been used to study their trans-influence on halides. The effects of experimental errors and packing have been evaluated and taken into account in the discussion of the cis- and trans-influence. X-ray diffraction data for structural analysis were collected on a four-circle diffractometer with MoKa radiation. Comparisons of related structures were performed with statistical methods such as half-normal probability plot... (More)
- Single crystal structural data have been used to estimate the influence of the X, Y and Z ligands on the Pt‹L bond length in [PtLXYZ] complexes, i.e. the ground state cis- and trans-influence. Cl or S were selected as indicator ligands, L, for these studies. Ligands with soft donor atoms, such as sulfur, carbon and silicon have been used to study their trans-influence on halides. The effects of experimental errors and packing have been evaluated and taken into account in the discussion of the cis- and trans-influence. X-ray diffraction data for structural analysis were collected on a four-circle diffractometer with MoKa radiation. Comparisons of related structures were performed with statistical methods such as half-normal probability plot analysis and calculations of average bond distances and their dispersions. These comparisons reveal that particularly the packing effects can affect the bond distances to a significant extent. A "noise level" for the combined outcome of experimental errors and packing effects is proposed. Differences in corresponding Pt‹Cl as well as Pt‹S distances in different compounds are considered possibly significant (above the noise level) in the range 0.01-0.02 Å and as significant if the difference is larger than 0.02 Å. These levels of significance are sometimes too optimistic but in most cases they can be considered as guide-lines. Some trans-complexes with a biological activity have been structurally characterized and their cytotoxicity investigated. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/28225
- author
- Lövqvist, Karin
- supervisor
- opponent
-
- Søtofte, Inger, Technical University of Denmark
- publishing date
- 1996
- type
- Thesis
- publication status
- published
- subject
- keywords
- Oorganisk kemi, Inorganic chemistry, X-ray diffraction, single crystal, structure determination, platinum(II), ligands, trans-influence, cis-influence
- pages
- 54 pages
- publisher
- Inorganic Chemistry, Chemical Center, Lund University
- defense location
- sal F, Chemical Center
- defense date
- 1996-03-22 10:15:00
- external identifiers
-
- other:ISRN: LUN KDL/NKKO--96/1027--SE
- language
- English
- LU publication?
- no
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Inorganic chemistry (ceased) (LUR000010)
- id
- 1ea2575e-e140-4954-8fcf-e6e1e5774b2e (old id 28225)
- date added to LUP
- 2016-04-04 12:01:05
- date last changed
- 2018-11-21 21:08:32
@phdthesis{1ea2575e-e140-4954-8fcf-e6e1e5774b2e, abstract = {{Single crystal structural data have been used to estimate the influence of the X, Y and Z ligands on the Pt‹L bond length in [PtLXYZ] complexes, i.e. the ground state cis- and trans-influence. Cl or S were selected as indicator ligands, L, for these studies. Ligands with soft donor atoms, such as sulfur, carbon and silicon have been used to study their trans-influence on halides. The effects of experimental errors and packing have been evaluated and taken into account in the discussion of the cis- and trans-influence. X-ray diffraction data for structural analysis were collected on a four-circle diffractometer with MoKa radiation. Comparisons of related structures were performed with statistical methods such as half-normal probability plot analysis and calculations of average bond distances and their dispersions. These comparisons reveal that particularly the packing effects can affect the bond distances to a significant extent. A "noise level" for the combined outcome of experimental errors and packing effects is proposed. Differences in corresponding Pt‹Cl as well as Pt‹S distances in different compounds are considered possibly significant (above the noise level) in the range 0.01-0.02 Å and as significant if the difference is larger than 0.02 Å. These levels of significance are sometimes too optimistic but in most cases they can be considered as guide-lines. Some trans-complexes with a biological activity have been structurally characterized and their cytotoxicity investigated.}}, author = {{Lövqvist, Karin}}, keywords = {{Oorganisk kemi; Inorganic chemistry; X-ray diffraction; single crystal; structure determination; platinum(II); ligands; trans-influence; cis-influence}}, language = {{eng}}, publisher = {{Inorganic Chemistry, Chemical Center, Lund University}}, title = {{A Crystallographic Study of Platinum(II) Complexes}}, year = {{1996}}, }