Testicular cancer and occupational exposure to polyvinyl chloride plastics: A case-control study
(2004) In International Journal of Cancer 109(3). p.425-429- Abstract
- Exposure to polyvinyl chloride. (PVC) plastics as a risk factor for testicular cancer was investigated. In total, 981 cases who were 20-75 years old and had reported to the Swedish Cancer Registry during 1993-1997 were included. One matched control from the population registry was used. Exposure was assessed by a questionnaire that was supplemented over the phone. Furthermore, an occupational hygienist qualified all exposures. In all, 791 matched pairs completed the questionnaire. Overall exposure to PVC plastics gave the odds ratio (OR)= 1.35, 95% confidence interval (Cl)= 1.06-1.71, increasing with > 10 year latency period to OR= 1.45, 95% Cl = 1.06-1.98. No dose-response relationships were found but rather an inverse relationship... (More)
- Exposure to polyvinyl chloride. (PVC) plastics as a risk factor for testicular cancer was investigated. In total, 981 cases who were 20-75 years old and had reported to the Swedish Cancer Registry during 1993-1997 were included. One matched control from the population registry was used. Exposure was assessed by a questionnaire that was supplemented over the phone. Furthermore, an occupational hygienist qualified all exposures. In all, 791 matched pairs completed the questionnaire. Overall exposure to PVC plastics gave the odds ratio (OR)= 1.35, 95% confidence interval (Cl)= 1.06-1.71, increasing with > 10 year latency period to OR= 1.45, 95% Cl = 1.06-1.98. No dose-response relationships were found but rather an inverse relationship with the highest odds ratios in the lowest exposure category. In conclusion, no clear association with testicular cancer and exposure to PVC could be found in our study in contrast to a previous observation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/286132
- author
- Hardell, L ; Malmqvist, N ; Ohlson, CG ; Westberg, H and Eriksson, Mikael LU
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- polyvinyl chloride, case-control study, exposure matrix, testicular, cancer
- in
- International Journal of Cancer
- volume
- 109
- issue
- 3
- pages
- 425 - 429
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000189245300016
- pmid:14961582
- scopus:1342288411
- pmid:14961582
- ISSN
- 0020-7136
- DOI
- 10.1002/ijc.11709
- language
- English
- LU publication?
- yes
- id
- c60ff540-2fa7-46ff-953e-8286546aab78 (old id 286132)
- date added to LUP
- 2016-04-01 12:17:33
- date last changed
- 2022-01-27 01:34:08
@article{c60ff540-2fa7-46ff-953e-8286546aab78, abstract = {{Exposure to polyvinyl chloride. (PVC) plastics as a risk factor for testicular cancer was investigated. In total, 981 cases who were 20-75 years old and had reported to the Swedish Cancer Registry during 1993-1997 were included. One matched control from the population registry was used. Exposure was assessed by a questionnaire that was supplemented over the phone. Furthermore, an occupational hygienist qualified all exposures. In all, 791 matched pairs completed the questionnaire. Overall exposure to PVC plastics gave the odds ratio (OR)= 1.35, 95% confidence interval (Cl)= 1.06-1.71, increasing with > 10 year latency period to OR= 1.45, 95% Cl = 1.06-1.98. No dose-response relationships were found but rather an inverse relationship with the highest odds ratios in the lowest exposure category. In conclusion, no clear association with testicular cancer and exposure to PVC could be found in our study in contrast to a previous observation.}}, author = {{Hardell, L and Malmqvist, N and Ohlson, CG and Westberg, H and Eriksson, Mikael}}, issn = {{0020-7136}}, keywords = {{polyvinyl chloride; case-control study; exposure matrix; testicular; cancer}}, language = {{eng}}, number = {{3}}, pages = {{425--429}}, publisher = {{John Wiley & Sons Inc.}}, series = {{International Journal of Cancer}}, title = {{Testicular cancer and occupational exposure to polyvinyl chloride plastics: A case-control study}}, url = {{http://dx.doi.org/10.1002/ijc.11709}}, doi = {{10.1002/ijc.11709}}, volume = {{109}}, year = {{2004}}, }