Prognostic importance of new small Q waves following non-ST-elevation acute coronary syndromes
(2003) In American Journal of Medicine 115(8). p.613-619- Abstract
- PURPOSE: to investigate the prognostic importance of new small Q waves following an acute coronary syndrome. METHODS: We assessed 6-month mortality in 10,501 patients with non-ST-elevation acute coronary syndromes who had survived 30 days and had both admission and 30-day electrocardiograms. Patients were stratified by whether they had no new Q waves (n = 9447), new 30- to 40-ms Q waves (n = 733), or new greater than or equal to40-ms Q waves (n = 321). RESULTS: Mortality was higher in patients with 30- to 40-ms Q waves than in those with no new Q waves (3.4% [25/733] vs. 2.4% [227/9447], P = 0.005), and even higher in those with greater than or equal to40-ms Q waves (5.3% [17/321], P = 0.002). After adjustment for baseline risk predictors,... (More)
- PURPOSE: to investigate the prognostic importance of new small Q waves following an acute coronary syndrome. METHODS: We assessed 6-month mortality in 10,501 patients with non-ST-elevation acute coronary syndromes who had survived 30 days and had both admission and 30-day electrocardiograms. Patients were stratified by whether they had no new Q waves (n = 9447), new 30- to 40-ms Q waves (n = 733), or new greater than or equal to40-ms Q waves (n = 321). RESULTS: Mortality was higher in patients with 30- to 40-ms Q waves than in those with no new Q waves (3.4% [25/733] vs. 2.4% [227/9447], P = 0.005), and even higher in those with greater than or equal to40-ms Q waves (5.3% [17/321], P = 0.002). After adjustment for baseline risk predictors, mortality remained higher in patients with new 30- to 40-ms Q waves (odds ratio [OR] = 1.30; 95% confidence interval [CI]: 0.85 to 1.98; P = 0.23) and those with new greater than or equal to40-ms Q waves (OR = 1.87; 95% Cl: 1.13 to 3.09; P = 0.01). CONCLUSION: Patients with new small Q waves following a non-ST-elevation acute coronary syndrome are at increased risk of adverse outcomes. These small Q waves should be considered diagnostic of myocardial infarction. Further research should investigate whether even smaller QRS changes are prognostically important. (C)2003 by Excerpta Medica Inc. (Less)
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- author
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- American Journal of Medicine
- volume
- 115
- issue
- 8
- pages
- 613 - 619
- publisher
- Elsevier
- external identifiers
-
- pmid:14656613
- wos:000186883800003
- scopus:0345167961
- ISSN
- 0002-9343
- DOI
- 10.1016/j.amjmed.2003.08.007
- language
- English
- LU publication?
- yes
- id
- d3ff1e46-d22b-4da5-b111-9bcb2c8701d5 (old id 294005)
- date added to LUP
- 2016-04-01 15:41:32
- date last changed
- 2022-01-28 06:38:25
@article{d3ff1e46-d22b-4da5-b111-9bcb2c8701d5, abstract = {{PURPOSE: to investigate the prognostic importance of new small Q waves following an acute coronary syndrome. METHODS: We assessed 6-month mortality in 10,501 patients with non-ST-elevation acute coronary syndromes who had survived 30 days and had both admission and 30-day electrocardiograms. Patients were stratified by whether they had no new Q waves (n = 9447), new 30- to 40-ms Q waves (n = 733), or new greater than or equal to40-ms Q waves (n = 321). RESULTS: Mortality was higher in patients with 30- to 40-ms Q waves than in those with no new Q waves (3.4% [25/733] vs. 2.4% [227/9447], P = 0.005), and even higher in those with greater than or equal to40-ms Q waves (5.3% [17/321], P = 0.002). After adjustment for baseline risk predictors, mortality remained higher in patients with new 30- to 40-ms Q waves (odds ratio [OR] = 1.30; 95% confidence interval [CI]: 0.85 to 1.98; P = 0.23) and those with new greater than or equal to40-ms Q waves (OR = 1.87; 95% Cl: 1.13 to 3.09; P = 0.01). CONCLUSION: Patients with new small Q waves following a non-ST-elevation acute coronary syndrome are at increased risk of adverse outcomes. These small Q waves should be considered diagnostic of myocardial infarction. Further research should investigate whether even smaller QRS changes are prognostically important. (C)2003 by Excerpta Medica Inc.}}, author = {{Alexander, JH and Harrington, RA and Bhapkar, M and Mahaffey, KW and Lincoff, AM and Ohman, EM and Klootwijk, P and Pahlm, Olle and Henden, B and Deckers, JW and Simoons, ML and Califf, RM and Wagner, GS}}, issn = {{0002-9343}}, language = {{eng}}, number = {{8}}, pages = {{613--619}}, publisher = {{Elsevier}}, series = {{American Journal of Medicine}}, title = {{Prognostic importance of new small Q waves following non-ST-elevation acute coronary syndromes}}, url = {{http://dx.doi.org/10.1016/j.amjmed.2003.08.007}}, doi = {{10.1016/j.amjmed.2003.08.007}}, volume = {{115}}, year = {{2003}}, }