Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum.
(1988) In Arthritis and Rheumatism 31(8). p.1041-1045- Abstract
- Synovial fluids from 6 of 12 patients with rheumatoid arthritis (RA) and from 3 of 11 patients with reactive arthritis contained measurable levels of tumor necrosis factor α (TNFα). Seven of 12 sera from RA patients contained TNFα, while only 1 of those from reactive arthritis patients was positive. Gamma-interferon was detected in the synovial fluids and sera of only the RA patients. Tumor necrosis factor β was not detected in any sera or synovial fluids. RA patients with detectable TNFα had higher erythrocyte sedimentation rates and synovial fluid leukocyte counts.
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https://lup.lub.lu.se/record/2cb0f821-d861-4ad3-a2c0-cea40268079a
- author
- Saxne, Tore LU ; Palladino, Michael ; Heinegård, Dick LU ; Talal, Norman and Wollheim, Frank LU
- organization
- publishing date
- 1988
- type
- Contribution to journal
- publication status
- published
- in
- Arthritis and Rheumatism
- volume
- 31
- issue
- 8
- pages
- 1041 - 1045
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:0023712236
- ISSN
- 0004-3591
- language
- English
- LU publication?
- yes
- id
- 2cb0f821-d861-4ad3-a2c0-cea40268079a
- date added to LUP
- 2016-05-06 16:02:37
- date last changed
- 2021-03-21 05:26:46
@article{2cb0f821-d861-4ad3-a2c0-cea40268079a, abstract = {{Synovial fluids from 6 of 12 patients with rheumatoid arthritis (RA) and from 3 of 11 patients with reactive arthritis contained measurable levels of tumor necrosis factor α (TNFα). Seven of 12 sera from RA patients contained TNFα, while only 1 of those from reactive arthritis patients was positive. Gamma-interferon was detected in the synovial fluids and sera of only the RA patients. Tumor necrosis factor β was not detected in any sera or synovial fluids. RA patients with detectable TNFα had higher erythrocyte sedimentation rates and synovial fluid leukocyte counts.}}, author = {{Saxne, Tore and Palladino, Michael and Heinegård, Dick and Talal, Norman and Wollheim, Frank}}, issn = {{0004-3591}}, language = {{eng}}, number = {{8}}, pages = {{1041--1045}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Arthritis and Rheumatism}}, title = {{Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum.}}, volume = {{31}}, year = {{1988}}, }