A sol-gel integrated dual-readout microarray platform for quantification and identification of prostate-specific antigen
(2018) 28th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2017 2018-January.- Abstract
Here, we report a sol-gel integrated affinity microarray for on-chip matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which enables capture and identification of prostate-specific antigen (PSA) in samples. Protein microarray technologies, which involve miniaturizing spots of capture agents (such as antibody and aptamers) on a solid surface, enable multianalyte sensing and high-throughput analysis of protein-protein and protein-ligand interactions. This technique provides high-sensitivity analysis of biomarkers, as well as molecular profiling, and is thus used in the fields of life science, medicine and proteomics [1]. In clinical application, the high sensitive biomarker analysis enables early... (More)
Here, we report a sol-gel integrated affinity microarray for on-chip matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which enables capture and identification of prostate-specific antigen (PSA) in samples. Protein microarray technologies, which involve miniaturizing spots of capture agents (such as antibody and aptamers) on a solid surface, enable multianalyte sensing and high-throughput analysis of protein-protein and protein-ligand interactions. This technique provides high-sensitivity analysis of biomarkers, as well as molecular profiling, and is thus used in the fields of life science, medicine and proteomics [1]. In clinical application, the high sensitive biomarker analysis enables early diagnosis, and prediction of prognosis and the response to treatment [2,3].
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- author
- Lee, S. W. LU ; Lee, J. H. ; Kwon, H. G. ; Laurell, T. LU ; Jeong, O. C. and Kim, S.
- organization
- publishing date
- 2018-02-28
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- MHS 2017 - 28th 2017 International Symposium on Micro-NanoMechatronics and Human Science
- volume
- 2018-January
- pages
- 2 pages
- publisher
- IEEE - Institute of Electrical and Electronics Engineers Inc.
- conference name
- 28th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2017
- conference location
- Nagoya, Japan
- conference dates
- 2017-12-03 - 2017-12-06
- external identifiers
-
- scopus:85050544541
- ISBN
- 9781538633144
- DOI
- 10.1109/MHS.2017.8305253
- language
- English
- LU publication?
- yes
- id
- 2d7c217e-c90f-42ee-bc4b-ee0266fded8a
- date added to LUP
- 2018-09-18 12:04:54
- date last changed
- 2022-05-03 06:06:24
@inproceedings{2d7c217e-c90f-42ee-bc4b-ee0266fded8a, abstract = {{<p>Here, we report a sol-gel integrated affinity microarray for on-chip matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which enables capture and identification of prostate-specific antigen (PSA) in samples. Protein microarray technologies, which involve miniaturizing spots of capture agents (such as antibody and aptamers) on a solid surface, enable multianalyte sensing and high-throughput analysis of protein-protein and protein-ligand interactions. This technique provides high-sensitivity analysis of biomarkers, as well as molecular profiling, and is thus used in the fields of life science, medicine and proteomics [1]. In clinical application, the high sensitive biomarker analysis enables early diagnosis, and prediction of prognosis and the response to treatment [2,3].</p>}}, author = {{Lee, S. W. and Lee, J. H. and Kwon, H. G. and Laurell, T. and Jeong, O. C. and Kim, S.}}, booktitle = {{MHS 2017 - 28th 2017 International Symposium on Micro-NanoMechatronics and Human Science}}, isbn = {{9781538633144}}, language = {{eng}}, month = {{02}}, publisher = {{IEEE - Institute of Electrical and Electronics Engineers Inc.}}, title = {{A sol-gel integrated dual-readout microarray platform for quantification and identification of prostate-specific antigen}}, url = {{http://dx.doi.org/10.1109/MHS.2017.8305253}}, doi = {{10.1109/MHS.2017.8305253}}, volume = {{2018-January}}, year = {{2018}}, }