The complete mitochondrial DNA sequence of the horse, Equus caballus: extensive heteroplasmy of the control region
(1994) In Gene 148(2). p.357-362- Abstract
- The sequence of the mitochondrial (mt) DNA of the horse (Equus caballus) was determined. The length of the sequence presented is 16 660 bp. This figure, however, is not absolute due to pronounced heteroplasmy caused by variable numbers of the motif GTGCACCT in the control region of different molecules. Boundaries of the 13 peptide-coding genes were determined by the presence of start and stop codons, and by analogy with other eutherian mtDNAs. Three genes (COIII, NADH3 and NADH4) were not terminated by a stop codon. Comparison among the peptide-coding genes of the horse and eight other mammals suggests that the boundaries of some mt genes should be redefined. The number of repeats in the control region was determined by sequencing 77... (More)
- The sequence of the mitochondrial (mt) DNA of the horse (Equus caballus) was determined. The length of the sequence presented is 16 660 bp. This figure, however, is not absolute due to pronounced heteroplasmy caused by variable numbers of the motif GTGCACCT in the control region of different molecules. Boundaries of the 13 peptide-coding genes were determined by the presence of start and stop codons, and by analogy with other eutherian mtDNAs. Three genes (COIII, NADH3 and NADH4) were not terminated by a stop codon. Comparison among the peptide-coding genes of the horse and eight other mammals suggests that the boundaries of some mt genes should be redefined. The number of repeats in the control region was determined by sequencing 77 different clones (20 direct plus 57 PCR clones). The number of repeats ranged from 2 to 29. There was a pronounced overrepresentation of clones with many repeats (22-27). Very few clones had a repeat number that was close to the mean number of repeats. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/31462
- author
- Xu, Xiufeng and Arnason, Úlfur
- publishing date
- 1994
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- base frequencies, Gene extents, repeated motifs
- in
- Gene
- volume
- 148
- issue
- 2
- pages
- 357 - 362
- publisher
- Elsevier
- external identifiers
-
- scopus:0028132144
- ISSN
- 1879-0038
- DOI
- 10.1016/0378-1119(94)90713-7
- language
- English
- LU publication?
- no
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Genetics (Closed 2011) (011005100)
- id
- 2c59d177-3f36-44be-8889-fd405060cf1b (old id 31462)
- date added to LUP
- 2016-04-01 15:42:29
- date last changed
- 2021-10-03 03:54:19
@article{2c59d177-3f36-44be-8889-fd405060cf1b, abstract = {{The sequence of the mitochondrial (mt) DNA of the horse (Equus caballus) was determined. The length of the sequence presented is 16 660 bp. This figure, however, is not absolute due to pronounced heteroplasmy caused by variable numbers of the motif GTGCACCT in the control region of different molecules. Boundaries of the 13 peptide-coding genes were determined by the presence of start and stop codons, and by analogy with other eutherian mtDNAs. Three genes (COIII, NADH3 and NADH4) were not terminated by a stop codon. Comparison among the peptide-coding genes of the horse and eight other mammals suggests that the boundaries of some mt genes should be redefined. The number of repeats in the control region was determined by sequencing 77 different clones (20 direct plus 57 PCR clones). The number of repeats ranged from 2 to 29. There was a pronounced overrepresentation of clones with many repeats (22-27). Very few clones had a repeat number that was close to the mean number of repeats.}}, author = {{Xu, Xiufeng and Arnason, Úlfur}}, issn = {{1879-0038}}, keywords = {{base frequencies; Gene extents; repeated motifs}}, language = {{eng}}, number = {{2}}, pages = {{357--362}}, publisher = {{Elsevier}}, series = {{Gene}}, title = {{The complete mitochondrial DNA sequence of the horse, Equus caballus: extensive heteroplasmy of the control region}}, url = {{http://dx.doi.org/10.1016/0378-1119(94)90713-7}}, doi = {{10.1016/0378-1119(94)90713-7}}, volume = {{148}}, year = {{1994}}, }