Bandpass Filtering of DNA Elastic Modes Using Confinement and Tension
Lin, Jun ; Persson, Fredrik ; Fritzsche, Joachim ; Tegenfeldt, Jonas LU
and Saleh, Omar A.
(2012)
In Biophysical Journal
102.
p.96-100
- Abstract
- During a variety of biological and technological processes, biopolymers are simultaneously subject to both confinement and external forces. Although significant efforts have gone into understanding the physics of polymers that are only confined, or only under tension, little work has been done to explore the effects of the interplay of force and confinement. Here, we study the combined effects of stretching and confinement on a polymer’s configurational freedom. We measure the elastic response of long double-stranded DNA molecules that are partially confined to thin, nanofabricated slits. We account for the data through a model in which the DNA’s short-wavelength transverse elastic modes are cut off by applied force and the DNA’s bending... (More)
- During a variety of biological and technological processes, biopolymers are simultaneously subject to both confinement and external forces. Although significant efforts have gone into understanding the physics of polymers that are only confined, or only under tension, little work has been done to explore the effects of the interplay of force and confinement. Here, we study the combined effects of stretching and confinement on a polymer’s configurational freedom. We measure the elastic response of long double-stranded DNA molecules that are partially confined to thin, nanofabricated slits. We account for the data through a model in which the DNA’s short-wavelength transverse elastic modes are cut off by applied force and the DNA’s bending stiffness, whereas long-wavelength modes are cut off by confinement. Thus, we show that confinement and stretching combine to permit tunable bandpass filtering of the elastic modes of long polymers. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3224893
- author
- Lin, Jun
; Persson, Fredrik
; Fritzsche, Joachim
; Tegenfeldt, Jonas
LU
and Saleh, Omar A.
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Biophysical Journal
- volume
- 102
- pages
- 96 - 100
- publisher
- Cell Press
- external identifiers
-
- wos:000298825400012
- scopus:84855443364
- pmid:22225802
- ISSN
- 1542-0086
- DOI
- 10.1016/j.bpj.2011.11.4014
- language
- English
- LU publication?
- yes
- id
- 2a34d629-c97f-4fe7-b136-e4b3ee4ec75c (old id 3224893)
- date added to LUP
- 2016-04-01 10:12:03
- date last changed
- 2022-04-27 19:37:56
@article{2a34d629-c97f-4fe7-b136-e4b3ee4ec75c,
abstract = {{During a variety of biological and technological processes, biopolymers are simultaneously subject to both confinement and external forces. Although significant efforts have gone into understanding the physics of polymers that are only confined, or only under tension, little work has been done to explore the effects of the interplay of force and confinement. Here, we study the combined effects of stretching and confinement on a polymer’s configurational freedom. We measure the elastic response of long double-stranded DNA molecules that are partially confined to thin, nanofabricated slits. We account for the data through a model in which the DNA’s short-wavelength transverse elastic modes are cut off by applied force and the DNA’s bending stiffness, whereas long-wavelength modes are cut off by confinement. Thus, we show that confinement and stretching combine to permit tunable bandpass filtering of the elastic modes of long polymers.}},
author = {{Lin, Jun and Persson, Fredrik and Fritzsche, Joachim and Tegenfeldt, Jonas and Saleh, Omar A.}},
issn = {{1542-0086}},
language = {{eng}},
pages = {{96--100}},
publisher = {{Cell Press}},
series = {{Biophysical Journal}},
title = {{Bandpass Filtering of DNA Elastic Modes Using Confinement and Tension}},
url = {{https://lup.lub.lu.se/search/files/1645330/3242331.pdf}},
doi = {{10.1016/j.bpj.2011.11.4014}},
volume = {{102}},
year = {{2012}},
}