Nanoparticles as pseudostationary phase in capillary electrochrornatography/ESI-MS
(2002) In Analytical Chemistry 74(18). p.4595-4601- Abstract
- A novel technique that uses polymer nanoparticles as pseudostationary phase in capillary electrochromatography with electrospray ionization mass spectrometry detection is described. A continuous full filling technique in which the nanoparticles were suspended in the entire electrolyte volume as well as a conventional partial filling technique is presented. No nanoparticles entered the mass spectrometer, which was fitted with an orthogonal electrospray interface, despite the continuous flow of nanoparticles into the interface. Nanoparticles (average diameter 160 nm) were prepared from methacrylic acid, methyl methacrylate, and trimethylolpropane trimethacrylate by utilizing a precipitation polymerization technique. Salbutamol,... (More)
- A novel technique that uses polymer nanoparticles as pseudostationary phase in capillary electrochromatography with electrospray ionization mass spectrometry detection is described. A continuous full filling technique in which the nanoparticles were suspended in the entire electrolyte volume as well as a conventional partial filling technique is presented. No nanoparticles entered the mass spectrometer, which was fitted with an orthogonal electrospray interface, despite the continuous flow of nanoparticles into the interface. Nanoparticles (average diameter 160 nm) were prepared from methacrylic acid, methyl methacrylate, and trimethylolpropane trimethacrylate by utilizing a precipitation polymerization technique. Salbutamol, nortriptyline, and diphenhydramine were used as analytes. The interaction between analytes and nanoparticles was found to be predominantly ionic. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/327689
- author
- Viberg, Peter LU ; Jornten-Karlsson, M ; Petersson, P ; Spégel, Peter LU and Nilsson, Staffan LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Analytical Chemistry
- volume
- 74
- issue
- 18
- pages
- 4595 - 4601
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- pmid:12349959
- wos:000178068000001
- scopus:0037106390
- ISSN
- 1520-6882
- DOI
- 10.1021/ac0204045
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004)
- id
- d99ef15c-e50d-49e7-85be-7a251e835e10 (old id 327689)
- date added to LUP
- 2016-04-01 12:38:00
- date last changed
- 2022-01-27 07:44:57
@article{d99ef15c-e50d-49e7-85be-7a251e835e10, abstract = {{A novel technique that uses polymer nanoparticles as pseudostationary phase in capillary electrochromatography with electrospray ionization mass spectrometry detection is described. A continuous full filling technique in which the nanoparticles were suspended in the entire electrolyte volume as well as a conventional partial filling technique is presented. No nanoparticles entered the mass spectrometer, which was fitted with an orthogonal electrospray interface, despite the continuous flow of nanoparticles into the interface. Nanoparticles (average diameter 160 nm) were prepared from methacrylic acid, methyl methacrylate, and trimethylolpropane trimethacrylate by utilizing a precipitation polymerization technique. Salbutamol, nortriptyline, and diphenhydramine were used as analytes. The interaction between analytes and nanoparticles was found to be predominantly ionic.}}, author = {{Viberg, Peter and Jornten-Karlsson, M and Petersson, P and Spégel, Peter and Nilsson, Staffan}}, issn = {{1520-6882}}, language = {{eng}}, number = {{18}}, pages = {{4595--4601}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Analytical Chemistry}}, title = {{Nanoparticles as pseudostationary phase in capillary electrochrornatography/ESI-MS}}, url = {{http://dx.doi.org/10.1021/ac0204045}}, doi = {{10.1021/ac0204045}}, volume = {{74}}, year = {{2002}}, }