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Population Trends in Percutaneous Coronary Intervention 20-Year Results From the SCAAR (Swedish Coronary Angiography and Angioplasty Registry)

Fokkema, Marieke L. ; James, Stefan K. ; Albertsson, Per ; Akerblom, Axel ; Calais, Fredrik ; Eriksson, Peter ; Jensen, Jens ; Nilsson, Tage ; de Smet, Bart J. and Sjogren, Iwar , et al. (2013) In Journal of the American College of Cardiology 61(12). p.1222-1230
Abstract
Objectives The aim of this study was to describe the characteristics and outcome of all consecutive patients treated with percutaneous coronary intervention (PCI) in an unselected nationwide cohort over the past 2 decades. Background Over the last 20 years, treatment with PCI has evolved dramatically, but the change in patient characteristics has not been well described. Methods We included all patients undergoing a PCI procedure for the first time between January 1990 and December 2010 from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry). Patients were divided into different cohorts on the basis of the year of the first PCI procedure. Results A total of 144,039 patients was included. The mean age increased from 60.1 +/-... (More)
Objectives The aim of this study was to describe the characteristics and outcome of all consecutive patients treated with percutaneous coronary intervention (PCI) in an unselected nationwide cohort over the past 2 decades. Background Over the last 20 years, treatment with PCI has evolved dramatically, but the change in patient characteristics has not been well described. Methods We included all patients undergoing a PCI procedure for the first time between January 1990 and December 2010 from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry). Patients were divided into different cohorts on the basis of the year of the first PCI procedure. Results A total of 144,039 patients was included. The mean age increased from 60.1 +/- 9.9 years in 1990 to 1995 to 67.1 +/- 11.2 years in 2009 to 2010. The proportion of patients presenting with unstable coronary artery disease and ST-segment elevation myocardial infarction increased from 27.4% and 6.2% to 47.7% and 32.5%, respectively. Diabetes mellitus and multivessel disease were more often present in the later-year cohorts. The 1-year mortality increased from 2.2% in 1990 to 1995 to 5.9% in 2009 to 2010, but after adjustment for age and indication, a modest decrease was shown, mainly in ST-segment elevation myocardial infarction patients. Conclusions Characteristics of PCI patients have changed substantially over time, reflecting the establishment of new evidence. The increasing age and proportion of patients undergoing PCI for acute coronary syndromes greatly influence outcome. Understanding the changing patient characteristics is important for the translation of evidence to real-world clinical practice. (J Am Coll Cardiol 2013; 61: 1222-30) (C) 2013 by the American College of Cardiology Foundation (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
coronary artery disease, percutaneous coronary intervention, population, trends
in
Journal of the American College of Cardiology
volume
61
issue
12
pages
1222 - 1230
publisher
Elsevier
external identifiers
  • wos:000316751100003
  • scopus:84877311650
  • pmid:23500325
ISSN
0735-1097
DOI
10.1016/j.jacc.2013.01.007
language
English
LU publication?
yes
id
d3bf36e3-52ce-4a28-9119-d759bc9a7ab8 (old id 3750172)
date added to LUP
2016-04-01 10:33:06
date last changed
2022-03-27 17:22:49
@article{d3bf36e3-52ce-4a28-9119-d759bc9a7ab8,
  abstract     = {{Objectives The aim of this study was to describe the characteristics and outcome of all consecutive patients treated with percutaneous coronary intervention (PCI) in an unselected nationwide cohort over the past 2 decades. Background Over the last 20 years, treatment with PCI has evolved dramatically, but the change in patient characteristics has not been well described. Methods We included all patients undergoing a PCI procedure for the first time between January 1990 and December 2010 from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry). Patients were divided into different cohorts on the basis of the year of the first PCI procedure. Results A total of 144,039 patients was included. The mean age increased from 60.1 +/- 9.9 years in 1990 to 1995 to 67.1 +/- 11.2 years in 2009 to 2010. The proportion of patients presenting with unstable coronary artery disease and ST-segment elevation myocardial infarction increased from 27.4% and 6.2% to 47.7% and 32.5%, respectively. Diabetes mellitus and multivessel disease were more often present in the later-year cohorts. The 1-year mortality increased from 2.2% in 1990 to 1995 to 5.9% in 2009 to 2010, but after adjustment for age and indication, a modest decrease was shown, mainly in ST-segment elevation myocardial infarction patients. Conclusions Characteristics of PCI patients have changed substantially over time, reflecting the establishment of new evidence. The increasing age and proportion of patients undergoing PCI for acute coronary syndromes greatly influence outcome. Understanding the changing patient characteristics is important for the translation of evidence to real-world clinical practice. (J Am Coll Cardiol 2013; 61: 1222-30) (C) 2013 by the American College of Cardiology Foundation}},
  author       = {{Fokkema, Marieke L. and James, Stefan K. and Albertsson, Per and Akerblom, Axel and Calais, Fredrik and Eriksson, Peter and Jensen, Jens and Nilsson, Tage and de Smet, Bart J. and Sjogren, Iwar and Thorvinger, Björn and Lagerqvist, Bo}},
  issn         = {{0735-1097}},
  keywords     = {{coronary artery disease; percutaneous coronary intervention; population; trends}},
  language     = {{eng}},
  number       = {{12}},
  pages        = {{1222--1230}},
  publisher    = {{Elsevier}},
  series       = {{Journal of the American College of Cardiology}},
  title        = {{Population Trends in Percutaneous Coronary Intervention 20-Year Results From the SCAAR (Swedish Coronary Angiography and Angioplasty Registry)}},
  url          = {{http://dx.doi.org/10.1016/j.jacc.2013.01.007}},
  doi          = {{10.1016/j.jacc.2013.01.007}},
  volume       = {{61}},
  year         = {{2013}},
}