Economic evaluation of the hydrolysis of lactose using immobilized beta-galactosidase
(1990) In Applied Biochemistry and Biotechnology 24-5. p.679-693- Abstract
- A computer program for preliminary cost estimates of free and immobilized enzyme systems has been developed. The cost for the hydrolysis of lactose by β-galactosidase fromAspergillus oryzae has been calculated for a batch tank reactor, with free (BTRF) and immobilized (BTRI) enzymes, a continuously stirred tank reactor (CSTR) and a plug-flow tubular reactor (PFTR), considering the mass transfer behavior and deactivation of the enzyme.
Enzyme immobilization is economically feasible, compared with a system with free enzymes, despite a very high cost for the enzyme attachment. At a half-life time of 80 d, the PFTR gives the lowest cost (0.48 SEK/kg lactose), but the cost for the BTRI is just slightly higher (0.66 SEK/kg... (More) - A computer program for preliminary cost estimates of free and immobilized enzyme systems has been developed. The cost for the hydrolysis of lactose by β-galactosidase fromAspergillus oryzae has been calculated for a batch tank reactor, with free (BTRF) and immobilized (BTRI) enzymes, a continuously stirred tank reactor (CSTR) and a plug-flow tubular reactor (PFTR), considering the mass transfer behavior and deactivation of the enzyme.
Enzyme immobilization is economically feasible, compared with a system with free enzymes, despite a very high cost for the enzyme attachment. At a half-life time of 80 d, the PFTR gives the lowest cost (0.48 SEK/kg lactose), but the cost for the BTRI is just slightly higher (0.66 SEK/kg lactose) and still much lower than the BTRF (2.10 SEK/kg lactose). (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3911611
- author
- Axelsson, Anders LU and Zacchi, Guido LU
- organization
- publishing date
- 1990
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Applied Biochemistry and Biotechnology
- volume
- 24-5
- pages
- 679 - 693
- publisher
- Humana Press
- external identifiers
-
- wos:A1990DE57300065
- scopus:0025157985
- ISSN
- 1559-0291
- DOI
- 10.1007/BF02920288
- language
- English
- LU publication?
- yes
- id
- ca14ae80-96ca-4d91-be08-27dbad7fb3f8 (old id 3911611)
- date added to LUP
- 2016-04-01 11:57:08
- date last changed
- 2023-11-11 07:09:57
@article{ca14ae80-96ca-4d91-be08-27dbad7fb3f8, abstract = {{A computer program for preliminary cost estimates of free and immobilized enzyme systems has been developed. The cost for the hydrolysis of lactose by β-galactosidase fromAspergillus oryzae has been calculated for a batch tank reactor, with free (BTRF) and immobilized (BTRI) enzymes, a continuously stirred tank reactor (CSTR) and a plug-flow tubular reactor (PFTR), considering the mass transfer behavior and deactivation of the enzyme.<br/><br> <br/><br> Enzyme immobilization is economically feasible, compared with a system with free enzymes, despite a very high cost for the enzyme attachment. At a half-life time of 80 d, the PFTR gives the lowest cost (0.48 SEK/kg lactose), but the cost for the BTRI is just slightly higher (0.66 SEK/kg lactose) and still much lower than the BTRF (2.10 SEK/kg lactose).}}, author = {{Axelsson, Anders and Zacchi, Guido}}, issn = {{1559-0291}}, language = {{eng}}, pages = {{679--693}}, publisher = {{Humana Press}}, series = {{Applied Biochemistry and Biotechnology}}, title = {{Economic evaluation of the hydrolysis of lactose using immobilized beta-galactosidase}}, url = {{http://dx.doi.org/10.1007/BF02920288}}, doi = {{10.1007/BF02920288}}, volume = {{24-5}}, year = {{1990}}, }