Intestinal carriage of p fimbriated escherichia coli and the susceptibility to urinary tract infection in young children
(1995) In Journal of Infectious Diseases 171(3). p.625-631- Abstract
This prospective study analyzed the intestinal carriage of P fimbriated Escherichia coli as a host susceptibility factor in urinary tract infection (UTI). P fimbriation was defined by the pap and G ad hesin (papG1A2prsGJ96)genotypes. Children with UTI carried pap+E. coli in the fecal flora more often than healthy controls both at diagnosis (86% vs. 29%) and during infection-free intervals (40%; P <.01). PI blood group-positive children carried pap+E. col in the fecal flora more often (88%) than those with P2 blood group (40%; P <.05). A pap+E. coli strain caused UTI in 53 of 55 patients who carried both pap+and pap–strains in their fecal flora. These... (More)
This prospective study analyzed the intestinal carriage of P fimbriated Escherichia coli as a host susceptibility factor in urinary tract infection (UTI). P fimbriation was defined by the pap and G ad hesin (papG1A2prsGJ96)genotypes. Children with UTI carried pap+E. coli in the fecal flora more often than healthy controls both at diagnosis (86% vs. 29%) and during infection-free intervals (40%; P <.01). PI blood group-positive children carried pap+E. col in the fecal flora more often (88%) than those with P2 blood group (40%; P <.05). A pap+E. coli strain caused UTI in 53 of 55 patients who carried both pap+and pap–strains in their fecal flora. These results suggest that persons who develop UTI have an increased tendency to carry pap+E. coli in the large intestine and that these pap+E. coli cause UTI more often than pap–E. coli strains in the fecal flora of the same host.
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- author
- Plos, Kaety ; Connell, Hugh LU ; Jodal, Ulf ; Marklund, Britt Inger ; Mårild, Staffan ; Wettergren, Björn and Svanborg, Catharina LU
- organization
- publishing date
- 1995-03
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Infectious Diseases
- volume
- 171
- issue
- 3
- pages
- 625 - 631
- publisher
- Oxford University Press
- external identifiers
-
- pmid:7876609
- scopus:0028935257
- ISSN
- 0022-1899
- DOI
- 10.1093/infdis/171.3.625
- language
- English
- LU publication?
- yes
- id
- 3d885cd1-9343-49b4-bc67-eee485a383b7
- date added to LUP
- 2019-06-19 14:10:43
- date last changed
- 2024-01-01 11:33:02
@article{3d885cd1-9343-49b4-bc67-eee485a383b7,
abstract = {{<p>This prospective study analyzed the intestinal carriage of P fimbriated Escherichia coli as a host susceptibility factor in urinary tract infection (UTI). P fimbriation was defined by the pap and G ad hesin (papG<sub>1A2</sub>prsG<sub>J96</sub>)genotypes. Children with UTI carried pap<sup>+</sup>E. coli in the fecal flora more often than healthy controls both at diagnosis (86% vs. 29%) and during infection-free intervals (40%; P <.01). PI blood group-positive children carried pap<sup>+</sup>E. col in the fecal flora more often (88%) than those with P2 blood group (40%; P <.05). A pap<sup>+</sup>E. coli strain caused UTI in 53 of 55 patients who carried both pap<sup>+</sup>and pap<sup>–</sup>strains in their fecal flora. These results suggest that persons who develop UTI have an increased tendency to carry pap<sup>+</sup>E. coli in the large intestine and that these pap<sup>+</sup>E. coli cause UTI more often than pap<sup>–</sup>E. coli strains in the fecal flora of the same host.</p>}},
author = {{Plos, Kaety and Connell, Hugh and Jodal, Ulf and Marklund, Britt Inger and Mårild, Staffan and Wettergren, Björn and Svanborg, Catharina}},
issn = {{0022-1899}},
language = {{eng}},
number = {{3}},
pages = {{625--631}},
publisher = {{Oxford University Press}},
series = {{Journal of Infectious Diseases}},
title = {{Intestinal carriage of p fimbriated escherichia coli and the susceptibility to urinary tract infection in young children}},
url = {{http://dx.doi.org/10.1093/infdis/171.3.625}},
doi = {{10.1093/infdis/171.3.625}},
volume = {{171}},
year = {{1995}},
}