γ-Tubulin⁻γ-Tubulin Interactions as the Basis for the Formation of a Meshwork
(2018) In International Journal of Molecular Sciences 19(10).- Abstract
In cytoplasm, protein γ-tubulin joins with various γ-tubulin complex proteins (GCPs) to form a heterotetramer γ-tubulin small complex (γ-TuSC) that can grow into a ring-shaped structure called the γ-tubulin ring complex (γ-TuRC). Both γ-TuSC and γ-TuRC are required for microtubule nucleation. Recent knowledge on γ-tubulin with regard to its cellular functions beyond participation in its creation of microtubules suggests that this protein forms a cellular meshwork. The present review summarizes the recognized functions of γ-tubulin and aims to unite the current views on this protein.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3fb22834-2aff-4f44-a777-7d3d130fc1c2
- author
- Rosselló, Catalina Ana LU ; Lindström, Lisa LU ; Eklund, Greta LU ; Corvaisier, Matthieu LU and Kristensson, Maria Alvarado LU
- organization
- publishing date
- 2018-10-19
- type
- Contribution to journal
- publication status
- published
- subject
- in
- International Journal of Molecular Sciences
- volume
- 19
- issue
- 10
- article number
- 3245
- publisher
- MDPI AG
- external identifiers
-
- scopus:85055183682
- pmid:30347727
- ISSN
- 1422-0067
- DOI
- 10.3390/ijms19103245
- language
- English
- LU publication?
- yes
- id
- 3fb22834-2aff-4f44-a777-7d3d130fc1c2
- date added to LUP
- 2018-10-24 14:33:27
- date last changed
- 2024-08-06 01:52:54
@article{3fb22834-2aff-4f44-a777-7d3d130fc1c2, abstract = {{<p>In cytoplasm, protein γ-tubulin joins with various γ-tubulin complex proteins (GCPs) to form a heterotetramer γ-tubulin small complex (γ-TuSC) that can grow into a ring-shaped structure called the γ-tubulin ring complex (γ-TuRC). Both γ-TuSC and γ-TuRC are required for microtubule nucleation. Recent knowledge on γ-tubulin with regard to its cellular functions beyond participation in its creation of microtubules suggests that this protein forms a cellular meshwork. The present review summarizes the recognized functions of γ-tubulin and aims to unite the current views on this protein.</p>}}, author = {{Rosselló, Catalina Ana and Lindström, Lisa and Eklund, Greta and Corvaisier, Matthieu and Kristensson, Maria Alvarado}}, issn = {{1422-0067}}, language = {{eng}}, month = {{10}}, number = {{10}}, publisher = {{MDPI AG}}, series = {{International Journal of Molecular Sciences}}, title = {{γ-Tubulin⁻γ-Tubulin Interactions as the Basis for the Formation of a Meshwork}}, url = {{http://dx.doi.org/10.3390/ijms19103245}}, doi = {{10.3390/ijms19103245}}, volume = {{19}}, year = {{2018}}, }