Generalized rank tests for replicated microarray data
(2005) In Statistical Applications in Genetics and Molecular Biology 4(1).- Abstract
- Gene expression data from microarray experiments have been studied using several statistical models. Significance Analysis of Microarrays (SAM), for example, has proved to be useful in analyzing microarray data. In the spirit of the SAM procedures, we develop permutation based rank-tests for generalized Wilcoxon ranksum test for two-group comparisons of replicated microarray data. Also, for microarray experiments with randomized block design, we consider generalized signed rank test. The statistical analysis software package is written in R and is freely available in a package.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/404730
- author
- Lee, MLT ; Gray, RJ ; Björkbacka, Harry LU and Freeman, MW
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- blocked comparisons, rank tests, permutation tests
- in
- Statistical Applications in Genetics and Molecular Biology
- volume
- 4
- issue
- 1
- publisher
- Berkeley Electronic Press
- external identifiers
-
- wos:000238478100035
- pmid:16646848
- scopus:19344376460
- ISSN
- 2194-6302
- language
- English
- LU publication?
- yes
- id
- 25fd86bb-9196-4884-90c6-930da65d5b6f (old id 404730)
- alternative location
- http://www.bepress.com/cgi/viewcontent.cgi?article=1093&context=sagmb
- date added to LUP
- 2016-04-01 12:33:02
- date last changed
- 2022-01-27 06:38:32
@article{25fd86bb-9196-4884-90c6-930da65d5b6f, abstract = {{Gene expression data from microarray experiments have been studied using several statistical models. Significance Analysis of Microarrays (SAM), for example, has proved to be useful in analyzing microarray data. In the spirit of the SAM procedures, we develop permutation based rank-tests for generalized Wilcoxon ranksum test for two-group comparisons of replicated microarray data. Also, for microarray experiments with randomized block design, we consider generalized signed rank test. The statistical analysis software package is written in R and is freely available in a package.}}, author = {{Lee, MLT and Gray, RJ and Björkbacka, Harry and Freeman, MW}}, issn = {{2194-6302}}, keywords = {{blocked comparisons; rank tests; permutation tests}}, language = {{eng}}, number = {{1}}, publisher = {{Berkeley Electronic Press}}, series = {{Statistical Applications in Genetics and Molecular Biology}}, title = {{Generalized rank tests for replicated microarray data}}, url = {{http://www.bepress.com/cgi/viewcontent.cgi?article=1093&context=sagmb}}, volume = {{4}}, year = {{2005}}, }