Enantioselective synthesis of anti-beta-amido-alpha-hydroxy esters via asymmetric transfer hydrogenation coupled with dynamic kinetic resolution
(2013) In Tetrahedron Letters 54(38). p.5266-5268- Abstract
- The asymmetric transfer hydrogenation of beta-amido-alpha-keto esters providing the corresponding anti-beta-amido-alpha-hydroxy esters via dynamic kinetic resolution is reported. The use of a commercially available, or simply prepared, chiral ruthenium catalyst results in good yields as well as high diastereoselectivities and enantioselectivities. (C) 2013 Elsevier Ltd. All rights reserved.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4062713
- author
- Villacrez, Marvin LU and Somfai, Peter LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Ruthenium, Dynamic kinetic resolution, Asymmetric transfer hydrogenation, Enantioselective, 1, 2-Amino alcohols
- in
- Tetrahedron Letters
- volume
- 54
- issue
- 38
- pages
- 5266 - 5268
- publisher
- Elsevier
- external identifiers
-
- wos:000323589300032
- scopus:84881609817
- ISSN
- 0040-4039
- DOI
- 10.1016/j.tetlet.2013.07.100
- language
- English
- LU publication?
- yes
- id
- 258ff45a-8b22-48eb-bfe0-85151b026e0a (old id 4062713)
- date added to LUP
- 2016-04-01 13:12:41
- date last changed
- 2024-04-10 02:11:05
@article{258ff45a-8b22-48eb-bfe0-85151b026e0a, abstract = {{The asymmetric transfer hydrogenation of beta-amido-alpha-keto esters providing the corresponding anti-beta-amido-alpha-hydroxy esters via dynamic kinetic resolution is reported. The use of a commercially available, or simply prepared, chiral ruthenium catalyst results in good yields as well as high diastereoselectivities and enantioselectivities. (C) 2013 Elsevier Ltd. All rights reserved.}}, author = {{Villacrez, Marvin and Somfai, Peter}}, issn = {{0040-4039}}, keywords = {{Ruthenium; Dynamic kinetic resolution; Asymmetric transfer hydrogenation; Enantioselective; 1; 2-Amino alcohols}}, language = {{eng}}, number = {{38}}, pages = {{5266--5268}}, publisher = {{Elsevier}}, series = {{Tetrahedron Letters}}, title = {{Enantioselective synthesis of anti-beta-amido-alpha-hydroxy esters via asymmetric transfer hydrogenation coupled with dynamic kinetic resolution}}, url = {{http://dx.doi.org/10.1016/j.tetlet.2013.07.100}}, doi = {{10.1016/j.tetlet.2013.07.100}}, volume = {{54}}, year = {{2013}}, }